Forkhead box protein FOXK1 disrupts the circadian rhythm to promote breast tumorigenesis in response to insulin resistance
Z Zhang, M Zhao, Q Wang, X Wang, Y Wang, Y Ge… - Cancer Letters, 2024 - Elsevier
The dysregulation of circadian rhythm oscillation is a prominent feature of various solid
tumors. Thus, clarifying the molecular mechanisms that maintain the circadian clock is …
tumors. Thus, clarifying the molecular mechanisms that maintain the circadian clock is …
[HTML][HTML] FOXK2 targeting by the SCF-E3 ligase subunit FBXO24 for ubiquitin mediated degradation modulates mitochondrial respiration
R El-Mergawy, L Chafin, JA Ovando-Ricardez… - Journal of Biological …, 2024 - Elsevier
FOXK2 is a crucial transcription factor implicated in a wide array of biological activities and
yet understanding of its molecular regulation at the level of protein turnover is limited. Here …
yet understanding of its molecular regulation at the level of protein turnover is limited. Here …
Single‐cell analysis of tumor microenvironment and cell adhesion reveals that interleukin‐1 beta promotes cancer cell proliferation in breast cancer
W Wang, G Dong, Z Yang, S Li, J Li… - Animal Models and …, 2024 - Wiley Online Library
Background Triple‐negative breast cancer (TNBC), which is so called because of the lack of
estrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor …
estrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor …