Individual response to ionizing radiation

N Foray, M Bourguignon, N Hamada - Mutation Research/Reviews in …, 2016 - Elsevier
The human response to ionizing radiation (IR) varies among individuals. The first evidence
of the individual response to IR was reported in the beginning of the 20th century …

Ionizing radiation induced cataracts: Recent biological and mechanistic developments and perspectives for future research

EA Ainsbury, S Barnard, S Bright, C Dalke… - … Research/Reviews in …, 2016 - Elsevier
The lens of the eye has long been considered as a radiosensitive tissue, but recent research
has suggested that the radiosensitivity is even greater than previously thought. The 2012 …

Noncancer effects of ionizing radiation exposure on the eye, the circulatory system and beyond: Developments made since the 2011 ICRP Statement on Tissue …

N Hamada - Radiation Research, 2023 - meridian.allenpress.com
For radiation protection purposes, noncancer effects with a threshold-type dose-response
relationship have been classified as tissue reactions (formerly called nonstochastic or …

An update on effects of ionizing radiation exposure on the eye

N Hamada, TV Azizova, MP Little - The British journal of …, 2020 - academic.oup.com
The International Commission on Radiological Protection (ICRP) has considered for over 60
years that the lens of the eye is among the most radiosensitive tissues, and has …

Intratumoral Biosynthesis of Gold Nanoclusters by Pancreatic Cancer to Overcome Delivery Barriers to Radiosensitization

AS Schwartz-Duval, Y Mackeyev, I Mahmud… - ACS …, 2024 - ACS Publications
Nanoparticle delivery to solid tumors is a prime challenge in nanomedicine. Here, we
approach this challenge through the lens of biogeochemistry, the field that studies the flow of …

[HTML][HTML] Cataractogenic load–a concept to study the contribution of ionizing radiation to accelerated aging in the eye lens

A Uwineza, AA Kalligeraki, N Hamada, M Jarrin… - … Research/Reviews in …, 2019 - Elsevier
Ionizing radiation (IR) damages DNA and other macromolecules, including proteins and
lipids. Most cell types can repair DNA damage and cycle continuously their macromolecules …

Ionizing radiation exposure: hazards, prevention, and biomarker screening

H Mu, J Sun, L Li, J Yin, N Hu, W Zhao, D Ding… - … Science and Pollution …, 2018 - Springer
Radiation is a form of energy derived from a source that is propagated through material in
space. It consists of ionizing radiation or nonionizing radiation. Ionizing radiation is a feature …

Inverse dose-rate effect of ionising radiation on residual 53BP1 foci in the eye lens

SGR Barnard, R McCarron, J Moquet, R Quinlan… - Scientific reports, 2019 - nature.com
The influence of dose rate on radiation cataractogenesis has yet to be extensively studied.
One recent epidemiological investigation suggested that protracted radiation exposure …

Ionizing radiation sensitivity of the ocular lens and its dose rate dependence

N Hamada - International Journal of Radiation Biology, 2017 - Taylor & Francis
Abstract Purpose: In 2011, the International Commission on Radiological Protection reduced
the threshold for the lens effects of low linear energy transfer (LET) radiation. On one hand …

Individual response of the ocular lens to ionizing radiation

SGR Barnard, N Hamada - International Journal of Radiation …, 2023 - Taylor & Francis
Purpose Cataract (opacification of the ocular lens) is a typical tissue reaction (deterministic
effect) following ionizing radiation exposure, for which prevention dose limits have been …