HTLV-1 Tax oncoprotein stimulates ROS production and apoptosis in T cells by interacting with
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Background Development of adult T-cell leukemia/lymphoma (ATL) involves human T-cell
leukemia virus type 1 (HTLV-1) infection and accumulation of somatic mutations. The most …

Adult T cell leukemia (ATL) cells show a mature helper-inducer T cell phenotype and are
thought to secrete many kinds of cytokines in vivo, complicating the clinical features in these …

Adult T‐cell leukemia (ATL) is a retrovirus‐associated leukemia with poor prognosis and
often has deletions of the p16INK4a and p15INK4b genes on chromosome 9p21. The gene …

Background Human T-cell leukemia virus type 1 (HTLV-1) infection is associated with adult
T-cell leukemia/lymphoma (ATLL), a lymphoproliferative malignancy with a dismal prognosis …

Background Human T-cell leukemia virus type 1 (HTLV-1) is associated with the
development of adult T-cell leukemia (ATL). HTLV-1 encoded Tax1 oncoprotein activates …

Abstract Interleukin-15 receptor (IL-15R) and IL-2R have the same β and γ chains, but IL-
15R has a specific α chain distinct from that of IL-2Rα, which is indispensable for the high …

Methylthioadenosine phosphorylase (MTAP) is an important enzyme used for the salvage of
adenine and methionine. Cells lacking this enzyme are expected to be sensitive to purine …

The production of salmonid leukocyte cell lines from primary cell cultures has been
attempted on several occasions, however, to date only monocyte/macrophage like cell lines …

Studies of FOXP3 expression have thus far focused on T cells, including both normal and
malignant T cells. In particular, adult T cell leukemia/lymphoma (ATLL) cells have been …