Background Food safety is a major global public health issue. The majority of traditional
culture-based methods have lengthy detection times, require sophisticated sample …

Background Agri-food safety has been considered as one of the most important public
concerns worldwide. From farm to table, food crops and foods are extremely vulnerable to …

The pandemic of COVID-19 creates an imperative need for sensitive and portable detection
of SARS-CoV-2. We devised a SERS-read, CRISPR/Cas-powered nanobioassay, termed as …

Reviewed are nucleic acid detection assays that incorporate clustered regularly interspaced
short palindromic repeats (CRISPR)-based diagnostics and microfluidic devices and …

The emerging monkeypox virus (MPXV) has raised global health concern, thereby
highlighting the need for rapid, sensitive, and easy-to-use diagnostics. Here, we develop a …

The continued emergence of SARS-CoV-2 variants of concern (VOCs) has raised great
challenges for epidemic prevention and control. A rapid, sensitive, and on-site SARS-CoV-2 …

Abstract clustered regularly interspaced short palindromic repeats (CRISPR)‐Cas systems
are increasingly used in biosensor development. However, directly translating recognition …

Recent advances in CRISPR-based biotechnologies have greatly expanded our capabilities
to repurpose CRISPR for the development of molecular diagnostic systems. The key …

Herein, for the first time, the CRISPR‐Cas12a system is combined with aptamer, cascaded
dynamic DNA network circuits, and Fe3O4@ hollow‐TiO2@ MoS2 nanochains (Fe3O4@ h …

Cell is the structural and functional unit of life. The manipulation of fluids and cells is of vital
importance in biotechnology, chemistry and biomedical areas. Microfluidics has provided a …