Classical active ingredients and extracts of Chinese herbal medicines: pharmacokinetics, pharmacodynamics, and molecular mechanisms for ischemic stroke
T Zhu, L Wang, Y Feng, G Sun… - Oxidative medicine and …, 2021 - Wiley Online Library
Stroke is a leading cause of death and disability worldwide, and approximately 87% of
cases are attributed to ischemia. The main factors that cause ischemic stroke include …
cases are attributed to ischemia. The main factors that cause ischemic stroke include …
The PI3K/AKT pathway—The potential key mechanisms of traditional Chinese medicine for stroke
C Gu, Q Zhang, Y Li, R Li, J Feng, W Chen… - Frontiers in …, 2022 - frontiersin.org
Stroke is associated with a high disability and fatality rate, and adversely affects the quality
of life of patients and their families. Traditional Chinese Medicine (TCM) has been used …
of life of patients and their families. Traditional Chinese Medicine (TCM) has been used …
[HTML][HTML] Notoginsenoside R1 activates the NAMPT-NAD+-SIRT1 cascade to promote postischemic angiogenesis by modulating Notch signaling
T Zhu, W Xie, L Wang, X Jin, X Meng, G Sun… - Biomedicine & …, 2021 - Elsevier
Nicotinamide phosphoribosyltransferase (NAMPT) maintains mitochondrial function and
protects against cerebral ischemic injury by improving energy metabolism. Notoginsenoside …
protects against cerebral ischemic injury by improving energy metabolism. Notoginsenoside …
From Seeds of Apium graveolens Linn. to a Cerebral Ischemia Medicine: The Long Journey of 3-n-Butylphthalide
J Marco-Contelles, Y Zhang - Journal of Medicinal Chemistry, 2020 - ACS Publications
3-n-Butylphthalide (NBP) as well as its derivatives and analogues (NBPs), in racemic or
enantiomerically pure forms, possess potent and diverse pharmacological properties and …
enantiomerically pure forms, possess potent and diverse pharmacological properties and …
Rapid characterization of the absorbed constituents in rat serum after oral administration and action mechanism of Naozhenning granule using LC–MS and network …
S Yu, H Liu, K Li, Z Qin, X Qin, P Zhu, Z Li - Journal of Pharmaceutical and …, 2019 - Elsevier
Naozhenning granule is a Chinese herbal formula, which is mainly used in the treatment of
concussion, cerebral post-traumatic syndrome. Although its effectiveness has been certified …
concussion, cerebral post-traumatic syndrome. Although its effectiveness has been certified …
DL‐3‐n‐butylphthalide suppressed autophagy and promoted angiogenesis in rats with vascular dementia by activating the Shh/Ptch1 signaling pathway
X Niu, M Li, Y Gao, G Xu, X Dong, B Chu, P Lv - Neuroscience Letters, 2021 - Elsevier
Abstract DL-3-n-butylphthalide (NBP) has neuroprotective effect on chronic cerebral
hypoperfusion animals. Here, we explored the role and underlying mechanism of NBP on …
hypoperfusion animals. Here, we explored the role and underlying mechanism of NBP on …
Nanowired delivery of DL-3-n-butylphthalide induces superior neuroprotection in concussive head injury
F Niu, A Sharma, L Feng, A Ozkizilcik… - Progress in Brain …, 2019 - Elsevier
Concussive head injury (CHI) is quite prevalent in military personnel leading to lifetime
disability in more than 85% of cases. Other reasons of CHI include motor vehicle accident …
disability in more than 85% of cases. Other reasons of CHI include motor vehicle accident …
丁苯酞注射液治疗急性脑梗死疗效及其对病人血清NT-proBNP 和Hcy 水平影响
李文娟， 李帅 - 蚌埠医学院学报, 2022 - xuebao.bbmu.edu.cn
丁苯酞注射液治疗急性脑梗死疗效及其对病人血清NT-proBNP和Hcy水平影响 高级检索 首页
期刊简介 期刊在线 1.优先发表 2.当期目录 3.过刊浏览 4.浏览排行 5.下载排行 6.被引排行 7.高级 …
期刊简介 期刊在线 1.优先发表 2.当期目录 3.过刊浏览 4.浏览排行 5.下载排行 6.被引排行 7.高级 …
[HTML][HTML] L-3-n-butylphthalide promotes restoration after an experimental animal model of intracerebral hemorrhage
Z Pi, J Liu, H Xiao, Z Hu - International Journal of Medical Sciences, 2021 - ncbi.nlm.nih.gov
Intracerebral hemorrhage (ICH) is a devastating type of stroke with high morbidity and
mortality, and the effective therapies for ICH remain to be explored. L-3-n-butylphthalide …
mortality, and the effective therapies for ICH remain to be explored. L-3-n-butylphthalide …
A study to decipher the potential effects of butylphthalide against central nervous system diseases based on network pharmacology and molecular docking integration …
Q Zhao, B Zheng, P Feng, X Li - … ‐Based Complementary and …, 2021 - Wiley Online Library
Background. Butylphthalide (NBP), approved by the China National Medical Products
Administration (NMPA) for the treatment of ischemic stroke (IS), showed pleiotropic …
Administration (NMPA) for the treatment of ischemic stroke (IS), showed pleiotropic …