Abstract Vascular Endothelial Growth Factor (VEGF) has a greater impact on
carcinogenesis, and it is the most significant receptor in mediating the mutagenesis and …

Eleven two-carbon tethered artemisinin–isatin hybrids (4a–k) were designed, synthesized,
and evaluated for their antiproliferative activity against MCF-7, MDA-MB-231, and MDA-MB …

Aromatase, a cytochrome P450 enzyme, is responsible for the conversion of androgens to
estrogens, which fuel the multiplication of cancerous cells. Inhibition of estrogen …

Abstract Coronavirus disease 2019 (COVID-19) caused appalling conditions over the globe,
which is currently faced by the entire human population. One of the primary reasons behind …

This research aims to screen out the effective bioactive compounds from Coriander
(Coriandrum sativum L.), which may be novel potential inhibitors of Eubacterium rectale for …

Heparin and heparan sulfate are important glycosaminoglycans that can regulate the
activities of many vital proteins, especially the fibroblast growth factor (FGF) family. Because …

The compounds, 1H-Isochromene and pyran carbonitrile were synthesized from the
pyrazole aldehyde derivatives through efficient synthetic routes and characterization was …

Gamma secretase (GS) is an important therapeutic target in anticancer drug discovery.
Increased GS activity activates notch signaling pathway which is associated with cancer …

Context: An outbreak of the new coronavirus disease 2019 (COVID-19) was reported in
Wuhan, China, in December 2019, subsequently affecting countries worldwide and causing …

The novel coronavirus disease 19 (COVID-19) has resulted in an estimated 20 million
excess deaths and the recent resurgence of COVID-19 in China is predicted to result in up to …