[HTML][HTML] A hypothesis on designing strategy of effective RdRp inhibitors for the treatment of SARS-CoV-2
Vaccines are used as one of the major weapons for the eradication of pandemic. However,
the rise of different variants of the SARS-CoV-2 virus is creating doubts regarding the end of …
the rise of different variants of the SARS-CoV-2 virus is creating doubts regarding the end of …
[PDF][PDF] Discovery of natural anti-apoptotic protein inhibitor using molecular docking and MM-GBSA Approach: An anticancer intervention
Apoptosis is a programmed molecular phenomenon in normal cells, and" evading
apoptosis" is a hallmark of cancer. Overexpression of anti-apoptotic BCL-2 promotes cancer …
apoptosis" is a hallmark of cancer. Overexpression of anti-apoptotic BCL-2 promotes cancer …
Designing of neoepitopes based vaccine against breast cancer using integrated immuno and bioinformatics approach
Cancer is characterized by genetic instability due to accumulation of somatic mutations in
the genes which generate neoepitopes (mutated epitopes) for targeting by Cytotoxic T …
the genes which generate neoepitopes (mutated epitopes) for targeting by Cytotoxic T …
Computational approaches: Atom-based 3D-QSAR, molecular docking, ADME-Tox, MD simulation and DFT to find novel multi-targeted Anti-tubercular agents
D Panigrahi, SK Sahu - 2024 - researchsquare.com
Tuberculosis (TB) has become the biggest threat towards human society due to the rapid
rise in resistance of the causative bacteria Mycobacterium tuberculosis (MTB) against the …
rise in resistance of the causative bacteria Mycobacterium tuberculosis (MTB) against the …
[PDF][PDF] In Silico Exploration of Bisphosphonate Scaffolds as Potential Inhibitors of SARS-CoV-2 RdRp for COVID-19 and PASC
M Garg, M Sankaranarayanan, SS Vasan - 2023 - scholar.archive.org
The novel coronavirus disease (COVID-19) pandemic has resulted in over 720 million
confirmed cases and 7 million deaths worldwide, with insufficient treatment options …
confirmed cases and 7 million deaths worldwide, with insufficient treatment options …
[PDF][PDF] Molecular Docking, Synthesis and In Vitro Alpha Amylase Activities of Newer Generation Imidazolo-Pyrimidine Derivatives
V Sharma, P Panwar, P Verma, A Rahman, B Tomar… - 2024 - researchgate.net
Diabetes mellitus is a chronic disease in which the blood sugar level or blood glucose
reaches too high. Our body can make glucose, which also comes from our food. Insulin is a …
reaches too high. Our body can make glucose, which also comes from our food. Insulin is a …
Molecular Docking and Dynamics Identifies Potential Repurposed Drug Candidates for COVID-19 Studies
M Muzaffar-Ur-Rehman, C Suryakant, A Chandu… - 2023 - preprints.org
The novel coronavirus disease 19 (COVID-19) has resulted in an estimated 20 million
excess deaths and the recent resurgence of COVID-19 in China is predicted to result in up to …
excess deaths and the recent resurgence of COVID-19 in China is predicted to result in up to …
Atividade antimicrobiana da planta Azadirachta indica (nim indiano)–uma revisão integrativa.
EM Guedes, CMS de Mendonça… - Diversitas …, 2022 - diversitas.emnuvens.com.br
Azadirachta indica A. Juss, conhecida comumente como Nim indiano é uma planta exótica
asiática, que apresenta um grande potencial terapêutico. O Nim possui como principal …
asiática, que apresenta um grande potencial terapêutico. O Nim possui como principal …
[PDF][PDF] Identification of potential CDK 8 inhibitor from pyrimidine derivatives via In-Silico approach
PB Patil, ST Kumbhar - jmpas.com
Pyrimidinesare six-membered heterocyclic scaffold present naturally in nucleic acid
components and are promising leads for the synthesis of medicinally important compounds …
components and are promising leads for the synthesis of medicinally important compounds …
Identification of potential human chymase inhibitors using molecular docking and molecular dynamics simulation
A Rozindar, DBM Virupakshaiah… - Journal of Applied …, 2023 - journals.ansfoundation.org
Chymase is a hydrolase class of enzymes that involves hydrolysis of peptide bonds. It is
abundant in secretory granules of mast cells. Mast cell chymase is involved in the synthesis …
abundant in secretory granules of mast cells. Mast cell chymase is involved in the synthesis …