MicroRNAs (miRNAs) are small, non-coding RNAs found throughout the eukaryotes that
control the expression of a number of genes involved in commitment and differentiation of …

Granulocyte colony-stimulating factor receptor (GCSFR) is a critical regulator of
granulopoiesis. Studies have shown significant upregulation of GCSFR in a variety of …

The blood-brain barrier (BBB), composed of brain microvascular endothelial cells (BMEC)
that are tightly linked by tight junction (TJ) proteins, restricts the movement of molecules …

Simple Summary Lymphoproliferative disorders comprise a heterogeneous group of
hematological malignancies characterized by abnormal lymphocyte proliferation …

Carnosine, an endogenous dipeptide, has been found to have a plethora of medicinal
properties, such as antioxidant, antiageing, and chelating effects, but with one downside: a …

Abstract Acute Myeloid Leukemia (AML) is a hematopoietic progenitor/stem cell disorder in
which neoplastic myeloblasts are stopped at an immature stage of differentiation and lost the …

Besides mobilizing stem cells into the periphery, granulocyte colony-stimulating factor (G-
CSF) has been shown to influence various types of innate and adaptive immune cells. For …

An increasing number of variants of unknown significance are being identified in leukemia
patients with the application of deep sequencing and these include CSF3R cytoplasmic …

Studies on hematopoietic stem cells (HSCs) and leukemia stem cells (LSCs) have helped to
establish the paradigms of normal and cancer stem cell concepts. For both HSCs and LSCs …

Abstract Three annotated CSF3R mRNA splice variants have been described. CSF3R-V1 is
the wild-type receptor, while CSF3R-V4 is a truncated form increased in some patients with …