Neuropeptide Y (NPY), one of the most abundant neuropeptides in the body, is widely
expressed in the central and peripheral nervous systems and acts on the cardiovascular …

Chronic cough is a difficult to treat symptom of many respiratory and some non-respiratory
diseases, indicating that varied pathologies can underpin the development of chronic cough …

Introduction Bitter taste receptors (T2Rs) are G protein-coupled receptors identified on the
tongue but expressed all over the body, including in airway cilia and macrophages, where …

Bitter taste receptors (T2Rs) localize to airway motile cilia and initiate innate immune
responses in retaliation to bacterial quorum sensing molecules. Activation of cilia T2Rs …

To find a cure for cystic fibrosis, there has been tremendous progress in the development of
treatments that target the basic defect in the protein channel, CFTR. However, 10% of cystic …

Better management of head and neck squamous cell carcinomas (HNSCCs) requires a
clearer understanding of tumor biology and disease risk. Bitter taste receptors (T2Rs) have …

Cardiovascular disease is the leading cause of death worldwide. Endothelial dysfunction of
the arterial vasculature plays a pivotal role in cardiovascular pathogenesis. Nicotine …

Since the embryo, the nervous system and immune system have been interacting to regulate
each other's development and working together to resist harmful stimuli. However …

Bitter taste receptors (T2Rs) are G-protein-coupled receptors (GPCRs) expressed on the
tongue but also in various locations throughout the body, including on motile cilia within the …

Along with the significant elongation in the average life expectancy of patients with cystic
fibrosis (CF), there are still significant discrepancies in the height, weight, and body mass …