Background Polyphenols are a class of naturally sourced compounds with widespread
distribution and an extensive array of bioactivities. However, due to their complex …

Polyphenols are a group of secondary plant metabolites widely present in diets and have
antagonistic effects on some chronic metabolic diseases, like type 2 diabetes (T2D) and …

Hyperlipidemia is associated with lipid metabolic disorders, chronic inflammation, and
intestinal dysbiosis. Previous studies have shown that the metabolic improvement of high-fat …

In recent years, studies investigating the role of the gut microbiota in health and diseases
have increased enormously–making it essential to deepen and question the research …

The prevalence of obesity in the world is fearsomely climbing, which has brought about
heavy threats on human health and economic development. For coping with this problem …

Farnesoid X receptor (FXR) is a nuclear receptor for bile acids (BAs) that is widely
expressed in the intestine, liver and kidney. FXR has important regulatory impacts on a wide …

Drugs are bioactive compounds originally discovered from chemical structures present in
both the plant and animal kingdoms. These have the ability to interact with molecules found …

The gut microbiome is increasingly recognized as a vital organ that participates in nutrient
acquisition, energy regulation and maintenance of human health. Targeted manipulation of …

Abstract Background Black chokeberry (Aronia melanocarpa (Micht.) Elliot) is a great dietary
source of a wide range of biologically active compounds, such as anthocyanins, flavonoids …

Chronic low-grade inflammation is regarded to an important signature of atherosclerosis
(AS). Macrophage (Mψ) and related polarization have been demonstrated to play a crucial …