Biosimilars in Inflammatory Bowel Disease 2017: State of the Science, State of the Art, and State of the Finances

CY Ha, A Kornbluth - Treatment of Inflammatory Bowel Disease with …, 2018 - Springer
Biosimilars are defined as highly similar but not chemically identical to the original (also
known as the reference) biologic drug. In order to obtain regulatory approval, an anti-TNF …

[PDF][PDF] Improving the clinical pathway for Crohn's perianal fistulas: novel approaches to aetiopathogenesis, treatment and outcome measurement

S Adegbola - 2021 - core.ac.uk
Crohn's perianal fistulas are often complex and represent a challenging and disabling
disease phenotype with unknown optimal treatment strategy. There are paucities in …

[PDF][PDF] COVİD-19 da Sitokinler ve COVİD-19 Tedavisinde Kullanılan İlaçlar Arasında Potansiyel İlaç Etkileşimleri Potential Interactions between Increased Cytokines in …

T Öztürk, T Gürpınar, Cİ Balaban, Y Tunçok - researchgate.net
Öz COVID-19 enfeksiyonu sırasında virus ve konakçı hücre etkileşimleri çok güçlü immun
mediyatörlerin akut üretimine yol açmaktadır. Ağır klinik durum çoğunlukla virüsün …

Retrospektive Analyse zum Vergleich des Einflusses einer frühen oder späten Intervention mit Tumornekrosefaktor-alpha-Antikörper-Therapie auf den …

T Seitz - 2020 - edoc.ub.uni-muenchen.de
Abstract Einleitung: TNFalpha-AK (TNF-AK) werden bei Morbus Crohn (MC) zunehmend
früher im Lauf der Erkrankung eingesetzt, da sie möglicherweise durch Verhinderung …

[PDF][PDF] Management of Primary Nonresponders and Partial Responders to Tumor Necrosis Factor-α Inhibitor Induction Therapy among Patients with Crohn's Disease

HITKM Nagasakac, S Shinzakia, KKYSM Watanabef - 2020 - e-helvetica.nb.admin.ch
Induction therapy with tumor necrosis factor-α (TNF-α) inhibitors is highly effective for the
treatment of Crohn's disease. However, there are primary nonresponders (PNR) of TNF-α …

Prognosis of IBD in children and adolescents: Assessment of outcome, based on clinical, serological and microbial markers at diagnosis

C Olbjørn - 2019 - duo.uio.no
Pediatric inflammatory bowel disease (IBD) patients often present with an extensive disease
distribution and an aggressive disease course. The disease course is unpredictable. We …

[PDF][PDF] Úloha genetických faktorů v diagnostice a predikci nespecifických střevních zánětů

MUDT Kupka - theses.cz
Crohnova nemoc je multifaktoriální zánětlivé onemocnění postihující zejména
gastrointestinální trakt. Z genetických faktorů uplatňujících se při rozvoji onemocnění jsou …

Investigating CD8+ T-cell gene expression signatures as disease prognostic biomarkers in paediatric inflammatory bowel disease.

M Gasparetto - 2019 - repository.cam.ac.uk
Background: Currently, it is not possible to predict disease behaviour for children with
inflammatory bowel disease (IBD), which is a major obstacle in an era where we strive to …

Full interchangeability in regards to immunogenicity between the infliximab reference biologic and biosimilars CT-P13 and SB2 in inflammatory bowel disease

KH Katsanos, K Papamichael… - Inflammatory Bowel …, 2018 - academic.oup.com
The introduction of biosimilars with similar efficacy and safety to the reference drug allows
for more cost-effective treatment options for patients with inflammatory bowel disease (IBD) …

Farmacovigilância dos Biossimilares em Portugal: o exemplo do Infliximab

SAG Barbosa - 2018 - repositorio.ul.pt
O biossimilar do Infliximab foi o primeiro da sua classe–anticorpos monoclonais–a surgir no
mercado, daí a sua importância para ajudar a compreender o comportamento deste tipo de …