Plasma medicine: Applications of cold atmospheric pressure plasma in dermatology

T Bernhardt, ML Semmler, M Schäfer… - Oxidative medicine …, 2019 - Wiley Online Library
The ability to produce cold plasma at atmospheric pressure conditions was the basis for the
rapid growth of plasma‐related application areas in biomedicine. Plasma comprises a …

Unraveling the crosstalk between melanoma and immune cells in the tumor microenvironment

M Marzagalli, ND Ebelt, ER Manuel - Seminars in cancer biology, 2019 - Elsevier
Cutaneous melanoma is the most common skin cancer with an incidence that has been
rapidly increasing in the past decades. Melanomas are among the most immunogenic …

[HTML][HTML] Cancer-associated fibroblasts neutralize the anti-tumor effect of CSF1 receptor blockade by inducing PMN-MDSC infiltration of tumors

V Kumar, L Donthireddy, D Marvel, T Condamine… - Cancer cell, 2017 - cell.com
Tumor-associated macrophages (TAM) contribute to all aspects of tumor progression. Use of
CSF1R inhibitors to target TAM is therapeutically appealing, but has had very limited anti …

Natural products: an evolving role in future drug discovery

BB Mishra, VK Tiwari - European journal of medicinal chemistry, 2011 - Elsevier
The therapeutic areas of infectious diseases and oncology have benefited from abundant
scaffold diversity in natural products, able to interact with many specific targets within the cell …

Natural products to drugs: natural product-derived compounds in clinical trials

MS Butler - Natural product reports, 2008 - pubs.rsc.org
Covering: 2005 to 2007 Natural product and natural product-derived compounds that are
being evaluated in clinical trials or are in registration (as at 31st December 2007) have been …

Ingenol mebutate gel for actinic keratosis

M Lebwohl, N Swanson, LL Anderson… - … England Journal of …, 2012 - Mass Medical Soc
Background Actinic keratosis is a common precursor to sun-related squamous-cell
carcinoma. Treating actinic keratoses and the surrounding skin area (ie, field therapy) can …

Topical treatments for skin cancer

JK Cullen, JL Simmons, PG Parsons… - Advanced drug delivery …, 2020 - Elsevier
Skin cancer is a broad term used to describe a number of different malignant indications of
the skin. Skin cancers mostly comprise of the keratinocyte cancers [Basal Cell Carcinoma …

Activation of Toll-like receptor 5 on breast cancer cells by flagellin suppresses cell proliferation and tumor growth

Z Cai, A Sanchez, Z Shi, T Zhang, M Liu, D Zhang - Cancer research, 2011 - AACR
Increasing evidence showed that Toll-like receptors (TLR), key receptors in innate immunity,
play a role in cancer progression and development but activation of different TLRs might …

[HTML][HTML] Neutrophils in gliomas

M Massara, P Persico, O Bonavita… - Frontiers in …, 2017 - frontiersin.org
Neutrophils are the most abundant white blood cells and are the first recruited to
inflammatory sites. Neutrophils are an important component of the tumor stroma and can …

Neutrophil elastase and neutrophil extracellular traps in the tumor microenvironment

H Huang, H Zhang, AE Onuma, A Tsung - Tumor Microenvironment: State …, 2020 - Springer
Tumor-associated neutrophils (TANs) play a major role during cancer development and
progression in the tumor microenvironment. Neutrophil elastase (NE) is a serine protease …