Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel human
coronavirus that has sparked a global pandemic of the coronavirus disease of 2019 (COVID …

The complement system consists of a network of plasma and membrane proteins that
modulate tissue homeostasis and contribute to immune surveillance by interacting with the …

Gangliosides are structurally and functionally polymorphic sialic acid containing
glycosphingolipids that are widely distributed in the human body. They play important roles …

Obsessive-compulsive disorder (OCD) is a highly disabling mental illness that can be
divided into frequent primary and rarer organic secondary forms. Its association with …

In recent years, new antibodies have been discovered which mediate autoimmune
encephalitis. This immunological response can be triggered by an infection or a tumor …

Epilepsy is a major health burden, calling for new mechanistic insights and therapies.
CRISPR-mediated gene editing shows promise to cure genetic pathologies, although …

Background: Glioblastoma multiforme is a malignant intracranial neoplasm that constitutes a
therapeutic challenge because of the associated high morbidity and mortality given the lack …

Lymphocytes cross vascular boundaries via either disrupted tight junctions (TJs) or caveolae
to induce tissue inflammation. In the CNS, Th17 lymphocytes cross the blood-brain barrier …

Increasing recognition of the role of B cells in the adaptive immune response makes B cells
an important therapeutic target in autoimmunity. Numerous current and developmental …

Movement, behavioral, and neuropsychiatric disorders in children have been linked to
infections and a group of anti-neuronal autoantibodies, implying dopamine receptor …