Inflammation in prostate carcinogenesis

AM De Marzo, EA Platz, S Sutcliffe, J Xu… - Nature Reviews …, 2007 - nature.com
About 20% of all human cancers are caused by chronic infection or chronic inflammatory
states. Recently, a new hypothesis has been proposed for prostate carcinogenesis. It …

The controversial relationship between benign prostatic hyperplasia and prostate cancer: the role of inflammation

C De Nunzio, G Kramer, M Marberger, R Montironi… - European urology, 2011 - Elsevier
Abstract Context Prostate cancer (PCa) is the most common cancer in the adult male, and
benign prostatic hyperplasia (BPH) represents the most frequent urologic diagnosis in …

Associations of luminal and basal subtyping of prostate cancer with prognosis and response to androgen deprivation therapy

SG Zhao, SL Chang, N Erho, M Yu, J Lehrer… - JAMA …, 2017 - jamanetwork.com
Importance There is a clear need for a molecular subtyping approach in prostate cancer to
identify clinically distinct subgroups that benefit from specific therapies. Objectives To …

The correlation between metabolic syndrome and prostatic diseases

C De Nunzio, W Aronson, SJ Freedland… - European urology, 2012 - Elsevier
CONTEXT: Metabolic syndrome (MetS), a cluster of several metabolic abnormalities with a
high socioeconomic cost, is considered a worldwide epidemic. Recent epidemiologic and …

[HTML][HTML] Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts

L Zhuang, J Kim, RM Adam… - The Journal of …, 2005 - Am Soc Clin Investig
Lipid rafts are cholesterol-and sphingolipid-enriched microdomains in cell membranes that
regulate phosphorylation cascades originating from membrane-bound proteins. In this study …

A perspective on the evolving story of PSMA biology, PSMA-based imaging, and endoradiotherapeutic strategies

DS O'Keefe, DJ Bacich, SS Huang… - Journal of Nuclear …, 2018 - Soc Nuclear Med
In this review, we cover the evolution of knowledge on the biology of prostate-specific
membrane antigen (PSMA) and its translation to therapy. The usual key to discovery is a …

[PDF][PDF] Cancer causes and treatments

A Saini, M Kumar, S Bhatt, V Saini… - Int. J. Pharm. Sci. Res, 2020 - researchgate.net
Cancer is a genetic disorder that results from genetic or epigenetic alterations in the somatic
cells and has abnormal cell growth which may be spread to other body parts. In 2018, 18 …

Canine prostate carcinoma: epidemiological evidence of an increased risk in castrated dogs

E Teske, EC Naan, EM Van Dijk… - Molecular and cellular …, 2002 - Elsevier
The present retrospective study investigated the frequency of prostate carcinoma (PCA)
among prostate abnormalities in dogs and determined whether castration influences the …

Prostate cancer in dogs: comparative and clinical aspects

BE LeRoy, N Northrup - The Veterinary Journal, 2009 - Elsevier
The canine prostate gland shares many morphological and functional similarities with the
human prostate and dogs are the only other large mammals that commonly develop …

The role of isoflavones in the prevention of breast cancer and prostate cancer

T Pejčić, M Zeković, U Bumbaširević, M Kalaba, I Vovk… - Antioxidants, 2023 - mdpi.com
This narrative review summarizes epidemiological studies on breast cancer and prostate
cancer with an overview of their global incidence distribution to investigate the relationship …