Metabolic mechanisms for and treatment of NAFLD or NASH occurring after liver transplantation

A Lonardo, A Mantovani, S Petta, A Carraro… - Nature Reviews …, 2022 - nature.com
The rising tide of non-alcoholic fatty liver disease (NAFLD) associated with the obesity
epidemic is a major health concern worldwide. NAFLD—specifically its more advanced form …

[HTML][HTML] Pathogenetic Mechanisms of Liver-Associated Injuries, Management, and Current Challenges in COVID-19 Patients

M Naeem, N Bano, S Manzoor, A Ahmad, N Munawar… - Biomolecules, 2023 - mdpi.com
The global outbreak of COVID-19 possesses serious challenges and adverse impacts for
patients with progression of chronic liver disease and has become a major threat to public …

[HTML][HTML] Pharmacomicrobiomics in Pediatric Oncology: The Complex Interplay between Commonly Used Drugs and Gut Microbiome

D Leardini, F Venturelli, F Baccelli, S Cerasi… - International Journal of …, 2022 - mdpi.com
The gut microbiome (GM) has emerged in the last few years as a main character in several
diseases. In pediatric oncological patients, GM has a role in promoting the disease …

[HTML][HTML] Intestinal microbiota links to allograft stability after lung transplantation: A prospective cohort study

J Wu, C Li, P Gao, C Zhang, P Zhang, L Zhang… - … and Targeted Therapy, 2023 - nature.com
Whether the alternated microbiota in the gut contribute to the risk of allograft rejection (AR)
and pulmonary infection (PI) in the setting of lung transplant recipients (LTRs) remains …

[HTML][HTML] The role of microbiota in liver transplantation and liver transplantation-related biliary complications

U Wirth, T Jiang, J Schardey, K Kratz, M Li… - International Journal of …, 2023 - mdpi.com
Liver transplantation as a treatment option for end-stage liver diseases is associated with a
relevant risk for complications. On the one hand, immunological factors and associated …

Modulating microbiome-immune axis in the deployment-related chronic diseases of Veterans: report of an expert meeting

J Sun, MN Ince, C Abraham, T Barrett, LA Brenner… - 2023 - Taylor & Francis
The present report summarizes the United States Department of Veterans Affairs (VA) field-
based meeting titled “Modulating microbiome-immune axis in the deployment-related …

Oral antibiotics lower mycophenolate mofetil drug exposure, possibly by interfering with the enterohepatic recirculation: A case series

M Simoons, KAT Naipal, H de Jong… - Pharmacology …, 2023 - Wiley Online Library
Mycophenolate mofetil has an important role as immunosuppressive agent in solid organ
transplant recipients. Exposure to the active mycophenolic acid (MPA) can be monitored …

[HTML][HTML] The effect of the gut microbiota on transplanted kidney function

J Przybyciński, S Drożdżal, A Wilk… - International Journal of …, 2023 - mdpi.com
The intestinal microflora is extremely important, not only in the processes of absorption,
digestion and biosynthesis of vitamins, but also in shaping the immune and cognitive …

[HTML][HTML] Pharmacomicrobiomics of Classical Immunosuppressant Drugs: A Systematic Review

A Manes, T Di Renzo, L Dodani, A Reale, C Gautiero… - Biomedicines, 2023 - mdpi.com
The clinical response to classical immunosuppressant drugs (cIMDs) is highly variable
among individuals. We performed a systematic review of published evidence supporting the …

[HTML][HTML] Rapid intestinal and systemic metabolic reprogramming in an immunosuppressed environment

B Ma, SJ Gavzy, M France, Y Song, HW Lwin… - BMC microbiology, 2023 - Springer
Intrinsic metabolism shapes the immune environment associated with immune suppression
and tolerance in settings such as organ transplantation and cancer. However, little is known …