Biologically active quinoline and quinazoline alkaloids part I

XF Shang, SL Morris‐Natschke, YQ Liu… - Medicinal research …, 2018 - Wiley Online Library
Quinoline and quinazoline alkaloids, two important classes of N‐based heterocyclic
compounds, have attracted tremendous attention from researchers worldwide since the 19th …

Alkaloids from plants with antimalarial activity: a review of recent studies

PF Uzor - Evidence‐Based Complementary and Alternative …, 2020 - Wiley Online Library
Malaria is one of the major health problems in developing countries. The disease kills a
large number of people every year and also affects financial status of many countries …

A metal‐organic framework (MOF) Fenton nanoagent‐enabled nanocatalytic cancer therapy in synergy with autophagy inhibition

B Yang, L Ding, H Yao, Y Chen, J Shi - Advanced materials, 2020 - Wiley Online Library
Nanocatalytic medicine has been developed recently to trigger intratumoral generation of
highly toxic reactive oxygen species (ROS) for cancer therapy, which, unfortunately, suffers …

Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapies

VR Solomon, H Lee - European journal of pharmacology, 2009 - Elsevier
Chloroquine (CQ), N′-(7-chloroquinolin-4-yl)-N, N-diethyl-pentane-1, 4-diamine, is widely
used as an effective and safe anti-malarial and anti-rheumatoid agent. CQ was discovered …

Biologically active quinoline and quinazoline alkaloids part II

XF Shang, SL Morris‐Natschke… - Medicinal research …, 2018 - Wiley Online Library
To follow‐up on our prior Part I review, this Part II review summarizes and provides updated
literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009 …

[PDF][PDF] Recent progress in the synthesis of quinolines

VV Kouznetsov, LYV Méndez… - Current Organic …, 2005 - researchgate.net
Recent Progress in the Synthesis of Quinolines Page 1 Current Organic Chemistry, 2005, 9,
141-161 141 1385-2728/05 $50.00+.00 © 2005 Bentham Science Publishers Ltd. Recent …

Phenothiazine: the seven lives of pharmacology's first lead structure

MJ Ohlow, B Moosmann - Drug discovery today, 2011 - Elsevier
Rooted in the early days of organic dye chemistry, the phenothiazine structure and its
derivatives have since held a prominent place in pharmacology and biomedicine. Initially …

Primaquine revisited six decades after its discovery

N Vale, R Moreira, P Gomes - European journal of medicinal chemistry, 2009 - Elsevier
Primaquine was firstly synthesized in 1946 in the USA, and is the most representative
member of the anti-malarial 8-aminoquinolines. Six decades have passed and primaquine …

A combined transcriptome and proteome survey of malaria parasite liver stages

AS Tarun, X Peng, RF Dumpit… - Proceedings of the …, 2008 - National Acad Sciences
For 50 years since their discovery, the malaria parasite liver stages (LS) have been difficult
to analyze, impeding their utilization as a critical target for antiinfection vaccines and drugs …

Artemisinin, a miracle of traditional Chinese medicine

LY Kong, RX Tan - Natural Product Reports, 2015 - pubs.rsc.org
The 2015 Nobel Prize in Physiology or Medicine, shared by Professor Youyou Tu, focused
worldwide attention on artemisinin, a natural product antimalarial drug inspired by traditional …