Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease

FA Zucca, J Segura-Aguilar, E Ferrari, P Muñoz… - Progress in …, 2017 - Elsevier
There are several interrelated mechanisms involving iron, dopamine, and neuromelanin in
neurons. Neuromelanin accumulates during aging and is the catecholamine-derived …

Melanosomes: biogenesis, properties, and evolution of an ancient organelle

L D'Alba, MD Shawkey - Physiological reviews, 2019 - journals.physiology.org
Melanosomes are organelles that produce and store melanin, a widespread biological
pigment with a unique suite of properties including high refractive index, semiconducting …

Unraveling the structure and function of melanin through synthesis

W Cao, X Zhou, NC McCallum, Z Hu… - Journal of the …, 2021 - ACS Publications
Melanin is ubiquitous in living organisms across different biological kingdoms of life, making
it an important, natural biomaterial. Its presence in nature from microorganisms to higher …

Chemical Reactivities of ortho-Quinones Produced in Living Organisms: Fate of Quinonoid Products Formed by Tyrosinase and Phenoloxidase Action on Phenols …

S Ito, M Sugumaran, K Wakamatsu - International Journal of Molecular …, 2020 - mdpi.com
Tyrosinase catalyzes the oxidation of phenols and catechols (o-diphenols) to o-quinones.
The reactivities of o-quinones thus generated are responsible for oxidative browning of plant …

Current challenges in understanding melanogenesis: bridging chemistry, biological control, morphology, and function

JD Simon, D Peles, K Wakamatsu… - Pigment cell & melanoma …, 2009 - Wiley Online Library
Melanin is a natural pigment produced within organelles, melanosomes, located in
melanocytes. Biological functions of melanosomes are often attributed to the unique …

Monodisperse polymer capsules: tailoring size, shell thickness, and hydrophobic cargo loading via emulsion templating

J Cui, Y Wang, A Postma, J Hao… - Advanced Functional …, 2010 - Wiley Online Library
The preparation of monodisperse polymer (polydopamine, PDA) capsules by a one‐step
interfacial polymerization of dopamine onto dimethyldiethoxysilane (DMDES) emulsion …

Interactions of Melanin with Electromagnetic Radiation: From Fundamentals to Applications

W Xie, A Dhinojwala, NC Gianneschi… - Chemical …, 2024 - ACS Publications
Melanin, especially integumentary melanin, interacts in numerous ways with
electromagnetic radiation, leading to a set of critical functions, including radiation protection …

“Fifty shades” of black and red or how carboxyl groups fine tune eumelanin and pheomelanin properties

R Micillo, L Panzella, K Koike, G Monfrecola… - International journal of …, 2016 - mdpi.com
Recent advances in the chemistry of melanins have begun to disclose a number of important
structure-property-function relationships of crucial relevance to the biological role of human …

Pheomelanin‐induced oxidative stress: bright and dark chemistry bridging red hair phenotype and melanoma

A Napolitano, L Panzella, G Monfrecola… - Pigment cell & …, 2014 - Wiley Online Library
The complex interplay of genetic and epigenetic factors linking sun exposure to melanoma
in the red hair phenotype hinges on the peculiar physical and chemical properties of …

Iris colour and the risk of developing uveal melanoma

LE Houtzagers, APA Wierenga, AAM Ruys… - International Journal of …, 2020 - mdpi.com
Uveal melanoma (UM) is a global disease which especially occurs in elderly people. Its
incidence varies widely between populations, with the highest incidence among …