Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models

I Guzmán-Soto, C McTiernan, M Gonzalez-Gomez… - Iscience, 2021 - cell.com
Biofilm formation in living organisms is associated to tissue and implant infections, and it has
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …

Candida sp. Infections in Patients with Diabetes Mellitus

CF Rodrigues, ME Rodrigues, M Henriques - Journal of clinical medicine, 2019 - mdpi.com
Candidiasis has increased substantially worldwide over recent decades and is a significant
cause of morbidity and mortality, especially among critically ill patients. Diabetes mellitus …

An Update on Candida tropicalis Based on Basic and Clinical Approaches

DL Zuza-Alves, WP Silva-Rocha… - Frontiers in …, 2017 - frontiersin.org
Candida tropicalis has emerged as one of the most important Candida species. It has been
widely considered the second most virulent Candida species, only preceded by C. albicans …

Zinc prevents vaginal candidiasis by inhibiting expression of an inflammatory fungal protein

E Roselletti, E Pericolini, A Nore, P Takacs… - Science translational …, 2023 - science.org
Candida causes an estimated half-billion cases of vulvovaginal candidiasis (VVC) every
year. VVC is most commonly caused by Candida albicans, which, in this setting, triggers …

Candidalysin drives epithelial signaling, neutrophil recruitment, and immunopathology at the vaginal mucosa

JP Richardson, HME Willems, DL Moyes… - Infection and …, 2018 - Am Soc Microbiol
Unlike other forms of candidiasis, vulvovaginal candidiasis, caused primarily by the fungal
pathogen Candida albicans, is a disease of immunocompetent and otherwise healthy …

Candida albicans pathogenesis: fitting within the host-microbe damage response framework

MA Jabra-Rizk, EF Kong, C Tsui, MH Nguyen… - Infection and …, 2016 - Am Soc Microbiol
Historically, the nature and extent of host damage by a microbe were considered highly
dependent on virulence attributes of the microbe. However, it has become clear that disease …

[HTML][HTML] Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms

P Van Dijck, J Sjollema, BPA Cammue, K Lagrou… - Microbial Cell, 2018 - ncbi.nlm.nih.gov
Unlike superficial fungal infections of the skin and nails, which are the most common fungal
diseases in humans, invasive fungal infections carry high morbidity and mortality …

[HTML][HTML] The role of Lactobacillus species in the control of Candida via biotrophic interactions

I Zangl, IJ Pap, C Aspöck, C Schüller - Microbial Cell, 2020 - ncbi.nlm.nih.gov
Microbial communities have an important role in health and disease. Candida spp. are
ubiquitous commensals and sometimes opportunistic fungal pathogens of humans …

How Biofilm Growth Affects Candida-Host Interactions

EF Eix, JE Nett - Frontiers in Microbiology, 2020 - frontiersin.org
Candida spp. proliferate as surface-associated biofilms in a variety of clinical niches. These
biofilms can be extremely difficult to eradicate in healthcare settings. Cells within biofilm …

[HTML][HTML] Candida and its dual lifestyle as a commensal and a pathogen

M Cauchie, S Desmet, K Lagrou - Research in microbiology, 2017 - Elsevier
Candida spp. are part of the normal vaginal microflora in 20–30% of healthy women.
However, if the balance between these yeasts and the host is disturbed, Candida spp. can …