The comorbidity of pain and depression has been well established in the literature and is
associated with a greater burden to the individual and society than either condition alone …

Pharmacological treatment of pain in multiple sclerosis (MS) is challenging due to the many
underlying pathophysiological mechanisms. Few controlled trials show adequate pain …

Pain and depression are the most prevalent physical and psychological symptom-based
disorders, respectively, and co-occur 30 to 50% of the time. However, their reciprocal …

Objective Previous studies have shown that depressive and anxiety disorders are strongly
related to somatic symptoms, but much is unclear about the specificity of this association …

Although patients with a depressive disorder report often of pain, their sensitivity to
experimental pain is controversial, probably due to differences in sensory testing methods …

'An excellent book, the most objective short account I know of all the various approaches to
depression.'Anthony Storr Several years ago, Lewis Wolpert had a severe episode of …

Abstract Purpose of Review Chronic pain impacts millions of people in the USA. At the heart
of the problem of chronic pain remains the complex psychosocial aspects associated with …

BACKGROUND: Previous cross-sectional studies have shown an association between pain
and depression, but it is unclear which comes first. Our objectives were to determine the …

Background Cognitive decline is a major concern in patients with migraine. Depression,
anxiety, and/or poor sleep quality are well-known comorbidities of migraine, but available …

Pain and symptoms of depression and anxiety have been observed to co-exist in the
community-dwelling elderly. While depression and pain have been suggested to be …