Advances in mass spectrometry (MS) and data processing have led to discoveries in
regulation of cellular metabolism by using metabolomics and lipidomics approaches. 1, 2 …

Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …

Nutrition exerts considerable effects on health, and dietary interventions are commonly used
to treat diseases of metabolic aetiology. Although cancer has a substantial metabolic …

Metabolomics generates a profile of small molecules that are derived from cellular
metabolism and can directly reflect the outcome of complex networks of biochemical …

During the progression of pancreatic ductal adenocarcinoma (PDAC), heterogeneous
subclonal populations emerge that drive primary tumor growth, regional spread, distant …

Summary S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) link one-
carbon metabolism to methylation status. However, it is unknown whether regulation of SAM …

As long-lived post-mitotic cells, neurons employ unique strategies to resist pathogen
infection while preserving cellular function. Here, using a murine model of Zika virus (ZIKV) …

Activation of CD4+ T cells results in rapid proliferation and differentiation into effector and
regulatory subsets. CD4+ effector T cell (Teff)(Th1 and Th17) and Treg subsets are …

Poorly organized tumour vasculature often results in areas of limited nutrient supply and
hypoxia. Despite our understanding of solid tumour responses to hypoxia, how nutrient …

Successful metastasis requires the co-evolution of stromal and cancer cells. We used stable
isotope labeling of amino acids in cell culture coupled with quantitative, label-free …