[HTML][HTML] The emergence of Zika virus and its new clinical syndromes

TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …

[HTML][HTML] Viral emerging diseases: challenges in developing vaccination strategies

M Trovato, R Sartorius, L D'Apice, R Manco… - Frontiers in …, 2020 - frontiersin.org
In the last decades, a number of infectious viruses have emerged from wildlife or re-
emerged, generating serious threats to the global health and to the economy worldwide …

[HTML][HTML] An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

H Xia, H Luo, C Shan, AE Muruato, BTD Nunes… - Nature …, 2018 - nature.com
Virus–host interactions determine an infection outcome. The Asian lineage of Zika virus
(ZIKV), responsible for the recent epidemics, has fixed a mutation in the NS1 gene after …

Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS 1‐caspase‐1 axis

Y Zheng, Q Liu, Y Wu, L Ma, Z Zhang, T Liu, S Jin… - The EMBO …, 2018 - embopress.org
Viral infection triggers host innate immune responses, which primarily include the activation
of type I interferon (IFN) signaling and inflammasomes. Here, we report that Zika virus (ZIKV) …

[HTML][HTML] Current status of Zika virus vaccines: successes and challenges

A Pattnaik, BR Sahoo, AK Pattnaik - Vaccines, 2020 - mdpi.com
The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …

[HTML][HTML] Evolution of two major Zika virus lineages: implications for pathology, immune response, and vaccine development

JT Beaver, N Lelutiu, R Habib, I Skountzou - Frontiers in immunology, 2018 - frontiersin.org
Zika virus (ZIKV) became a public health emergency of global concern in 2015 due to its
rapid expansion from French Polynesia to Brazil, spreading quickly throughout the …

[HTML][HTML] Zika virus vaccines

P Abbink, KE Stephenson, DH Barouch - Nature Reviews Microbiology, 2018 - nature.com
The recent epidemic of Zika virus (ZIKV) in the Americas has revealed the devastating
consequences of ZIKV infection, particularly in pregnant women. Congenital Zika syndrome …

Microbiota dysbiosis influences immune system and muscle pathophysiology of dystrophin‐deficient mice

A Farini, L Tripodi, C Villa, F Strati… - EMBO molecular …, 2023 - embopress.org
Duchenne muscular dystrophy (DMD) is a progressive severe muscle‐wasting disease
caused by mutations in DMD, encoding dystrophin, that leads to loss of muscle function with …

Zika virus vaccine development: progress in the face of new challenges

MS Diamond, JE Ledgerwood… - Annual review of …, 2019 - annualreviews.org
Zika virus (ZIKV) emerged at a global level when it spread to the Americas and began
causing congenital malformations and microcephaly in 2015. A rapid response by …

[HTML][HTML] Zika virus vaccine: progress and challenges

C Shan, X Xie, PY Shi - Cell host & microbe, 2018 - cell.com
The explosive emergence of Zika virus has inspired a global effort to develop vaccines. Zika
virus, which is a flavivirus primarily transmitted by mosquitoes, can cause devastating …