The Molecular Mechanisms Used by Neisseria gonorrhoeae To Initiate Infection Differ between Men and Women

JL Edwards, MA Apicella - Clinical microbiology reviews, 2004 - Am Soc Microbiol
The molecular mechanisms used by the gonococcus to initiate infection exhibit gender
specificity. The clinical presentations of disease are also strikingly different upon comparison …

[HTML][HTML] Gonorrhea-an evolving disease of the new millennium

SA Hill, TL Masters, J Wachter - Microbial cell, 2016 - ncbi.nlm.nih.gov
Etiology, transmission and protection: Neisseria gonorrhoeae (the gonococcus) is the
etiological agent for the strictly human sexually transmitted disease gonorrhea. Infections …

[HTML][HTML] Human CEACAM1 is targeted by a Streptococcus pyogenes adhesin implicated in puerperal sepsis pathogenesis

EA Catton, DA Bonsor, C Herrera… - nature …, 2023 - nature.com
Life-threatening bacterial infections in women after childbirth, known as puerperal sepsis,
resulted in classical epidemics and remain a global health problem. While outbreaks of …

[HTML][HTML] Pathogenesis of Neisseria gonorrhoeae and the Host Defense in Ascending Infections of Human Fallopian Tube

JD Lenz, JP Dillard - Frontiers in immunology, 2018 - frontiersin.org
Neisseria gonorrhoeae is an obligate human pathogen that causes mucosal surface
infections of male and female reproductive tracts, pharynx, rectum, and conjunctiva …

[HTML][HTML] Estradiol-Treated Female Mice as Surrogate Hosts for Neisseria gonorrhoeae Genital Tract Infections

AE Jerse, H Wu, M Packiam, RA Vonck… - Frontiers in …, 2011 - frontiersin.org
Historically, animal modeling of gonorrhea has been hampered by the exclusive adaptation
of Neisseria gonorrhoeae to humans. Genital tract infection can be established in female …

A co‐operative interaction between Neisseria gonorrhoeae and complement receptor 3 mediates infection of primary cervical epithelial cells

JL Edwards, EJ Brown, S Uk‐Nham… - Cellular …, 2002 - Wiley Online Library
Little is known about the pathogenesis of gonococcal infection within the lower female
genital tract. We recently described the distribution of complement receptor 3 (CR3) on …

'Small'talk: Opa proteins as mediators of Neisseria–host-cell communication

CR Hauck, TF Meyer - Current opinion in microbiology, 2003 - Elsevier
Opa proteins are variable outer membrane proteins of Neisseria gonorrhoeae and Neisseria
meningitidis that mediate tight interaction of these pathogens with human cells. They have …

Galectin‐3 binds lactosaminylated lipooligosaccharides from Neisseria gonorrhoeae and is selectively expressed by mucosal epithelial cells that are infected

CM John, GA Jarvis, KV Swanson, H Leffler… - Cellular …, 2002 - Wiley Online Library
Galectins are a family of β‐galactoside binding proteins that have been proposed as host
receptors for bacteria because β‐galactoside carbohydrates are common in bacterial …

Neisseria gonorrhoeae physiology and pathogenesis

LR Green, J Cole, EFD Parga, JG Shaw - Advances in microbial physiology, 2022 - Elsevier
Neisseria gonorrhoeae is an obligate human pathogen that is the cause of the sexually
transmitted disease gonorrhoea. Recently, there has been a surge in gonorrhoea cases that …

[HTML][HTML] The Biology of Neisseria Adhesins

MC Hung, M Christodoulides - Biology, 2013 - mdpi.com
Members of the genus Neisseria include pathogens causing important human diseases
such as meningitis, septicaemia, gonorrhoea and pelvic inflammatory disease syndrome …