Effects of bisphosphonates on appendicular fracture repair in rodents

M Hadjiargyrou - Bone, 2022 - Elsevier
The balance between osteoclastic bone resorption and osteoblastic bone formation is
ultimately responsible for maintaining a structural and functional skeleton. Despite their …

Sequential VEGF and BMP-2 releasing PLA-PEG-PLA scaffolds for bone tissue engineering: I. Design and in vitro tests

S Eğri, N Eczacıoğlu - Artificial cells, nanomedicine, and …, 2017 - Taylor & Francis
Abstract Biodegradable PLA-PEG-PLA block copolymers were synthesized with desired
backbone structures and molecular weights using PEG20000. Rectangular scaffolds were …

Secreted frizzled related protein 1 is a target to improve fracture healing

T Gaur, JJ Wixted, S Hussain… - Journal of cellular …, 2009 - Wiley Online Library
Genetic studies have identified a high bone mass of phenotype in both human and mouse
when canonical Wnt signaling is increased. Secreted frizzled related protein 1 (sFRP1) is …

[HTML][HTML] Hypo-fractionation radiotherapy normalizes tumor vasculature in non-small cell lung cancer xenografts through the p-STAT3/HIF-1 alpha signaling pathway

F Tong, C Xiong, C Wei, Y Wang, Z Liang… - … Advances in Medical …, 2020 - ncbi.nlm.nih.gov
Background: Hypo-fractionation radiotherapy (HFRT) was considered to be an important
treatment for non-small cell lung cancer (NSCLC), but the radiobiological effects of HFRT on …

The evaluation of VEGF and HIF1α gene polymorphisms and multiple sclerosis susceptibility

M Saravani, M Rokni, M Mehrbani… - The journal of gene …, 2019 - Wiley Online Library
Background Multiple sclerosis (MS) is an autoimmune disease that leads to myelin sheath
destruction. Hypoxiainducible factor 1 (HIF1) has several roles in cells, such as inducing …

[HTML][HTML] Hypoxia preconditioning of human MSCs: a direct evidence of HIF-1α and collagen type XV correlation

E Lambertini, L Penolazzi, M Angelozzi… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Mesenchymal stromal cells (MSCs) hold considerable promise in bone
tissue engineering, but their poor survival and potency when in vivo implanted limits their …

Impaired functional capacity of polarised neonatal macrophages

S Dreschers, K Ohl, N Schulte, K Tenbrock… - Scientific reports, 2020 - nature.com
Neonatal sepsis is accompanied by impaired apoptotic depletion of monocytes and
macrophages (MΦ), aberrant cytokine production, impaired cell metabolism, and sustained …

Chronic morphine treatment inhibits LPS-induced angiogenesis: implications in wound healing

JL Martin, R Charboneau, RA Barke, S Roy - Cellular immunology, 2010 - Elsevier
Delayed wound healing is a chronic problem in opioid drug abusers. We investigated the
role chronic morphine plays on later stages of wound healing events using an angiogenesis …

Activating glucocorticoid receptor-ERK signaling pathway contributes to ginsenoside Rg1 protection against β-amyloid peptide-induced human endothelial cells …

J Yan, Q Liu, Y Dou, Y Hsieh, Y Liu, R Tao… - Journal of …, 2013 - Elsevier
The deposition of β-amyloid (Aβ) in neurons and vascular cells of the brain has been
characterized in Alzheimer's disease. Ginsenoside Rg1 (Rg1) is an active components in …

[HTML][HTML] IL-6 promotes FSH-induced VEGF expression through JAK/STAT3 signaling pathway in bovine granulosa cells

M Yang, L Wang, X Wang, X Wang, Z Yang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Vascular endothelial growth factor (VEGF) has been demonstrated to
play a pivotal role in the regulation of angiogenesis in ovarian follicular development …