Potential Therapeutic Applications of Plant‐Derived Alkaloids against Inflammatory and Neurodegenerative Diseases

B Aryal, BK Raut, S Bhattarai… - Evidence‐Based …, 2022 - Wiley Online Library
Alkaloids are a type of natural compound possessing different pharmacological activities.
Natural products, including alkaloids, which originate from plants, have emerged as …

Toxicological effect and molecular mechanism of the chiral neonicotinoid dinotefuran in honeybees

Q Zhang, L Fu, T Cang, T Tang, M Guo… - Environmental …, 2021 - ACS Publications
With the increasing demand for pollinating services, the wellness of honeybees has
received widespread attention. Recent evidence indicated honeybee health might be posed …

Sulphur-containing amino acids: protective role against free radicals and heavy metals

MB Colovic, VM Vasic, DM Djuric… - Current medicinal …, 2018 - ingentaconnect.com
Background: Sulphur is an abundant element in biological systems, which plays an
important role in processes essential for life as a constituent of proteins, vitamins and other …

Anticholinergics: theoretical and clinical overview

PS Nishtala, MS Salahudeen… - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Anticholinergics are a class of medicines that block the neurotransmitter,
acetylcholine, in the brain and peripheral tissues. Medicines with anticholinergic activity are …

[HTML][HTML] Near-instantaneous catalytic hydrolysis of organophosphorus nerve agents with zirconium-based MOF/hydrogel composites

K Ma, MC Wasson, X Wang, X Zhang, KB Idrees… - Chem Catalysis, 2021 - cell.com
Zirconium-based metal-organic frameworks (Zr-MOFs) with Lewis-acidic sites are potent
catalysts for degrading organophosphorus nerve agents. However, a volatile basic solution …

Benzofuran and indole: promising scaffolds for drug development in Alzheimer's disease

D Goyal, A Kaur, B Goyal - ChemMedChem, 2018 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disease with no clinically
accepted treatment to cure or halt its progression. The Food and Drug Administration has …

[HTML][HTML] Neuroprotective effect of cardamom oil against aluminum induced neurotoxicity in rats

ST Auti, YA Kulkarni - Frontiers in neurology, 2019 - frontiersin.org
Acetylcholinesterase (AChE) is an enzyme involved in the progression of Alzheimer's
disease (AD). Cardamom oil (CO) has been reported to have acetylcholinesterase inhibitory …

Multienzyme chemiluminescent foldable biosensor for on-site detection of acetylcholinesterase inhibitors

L Montali, MM Calabretta, A Lopreside, M D'Elia… - Biosensors and …, 2020 - Elsevier
The rapid hydrolysis of acetylcholine (ACh), one of the key neurotransmitters in the human
body, by the enzyme acetylcholinesterase (AChE) is fundamental for the termination of ACh …

Fish inhabiting rice fields: Bioaccumulation, oxidative stress and neurotoxic effects after pesticides application

AS Rossi, N Fantón, MP Michlig, MR Repetti… - Ecological …, 2020 - Elsevier
The present study aimed to evaluate the biological effects triggered by the application of a
current-use mixture of pesticides (the herbicide glyphosate, the insecticide bifenthrin, BF …

Behavioral and biochemical consequences of Danio rerio larvae exposure to polylactic acid bioplastic

JPJ de Oliveira, FN Estrela… - Journal of hazardous …, 2021 - Elsevier
The literature has largely shown the toxicity of petroleum-based PLA biomicroplastics
(PLABioMPs) and encouraged the production of alternative materials to replace their use …