Structure and therapeutic uses of butyrylcholinesterase: application in detoxification, Alzheimer's disease, and fat metabolism
S Xing, Q Li, B Xiong, Y Chen, F Feng… - Medicinal Research …, 2021 - Wiley Online Library
Structural information of butyrylcholinesterase (BChE) and its variants associated with
several diseases are discussed here. Pure human BChE has been proved safe and effective …
several diseases are discussed here. Pure human BChE has been proved safe and effective …
Acetylcholinesterase inhibitors (nerve agents) as weapons of mass destruction: History, mechanisms of action, and medical countermeasures
V Aroniadou-Anderjaska, JP Apland, TH Figueiredo… - …, 2020 - Elsevier
Nerve agents are organophosphorus acetylcholinesterase inhibitors. Acute exposure to
nerve agents can cause rapid death. In this review, we summarize the history of nerve agent …
nerve agents can cause rapid death. In this review, we summarize the history of nerve agent …
Recent advances in electrochemical biosensors based on enzyme inhibition for clinical and pharmaceutical applications
A large number of enzyme inhibitors are used as drugs to treat several diseases such as
gout, diabetes, AIDS, depression, Parkinson's and Alzheimer's diseases. Electrochemical …
gout, diabetes, AIDS, depression, Parkinson's and Alzheimer's diseases. Electrochemical …
[HTML][HTML] Current and novel therapeutic molecules and targets in Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disorder in which the death of brain cells
causes memory loss and cognitive decline, ie, dementia. The disease starts with mild …
causes memory loss and cognitive decline, ie, dementia. The disease starts with mild …
Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments: a network meta‐analysis
SD Shenkin, J Hewitt, TJ Quinn - Cochrane Database of …, 2021 - cochranelibrary.com
Background Vascular cognitive impairment (VCI) describes a broad spectrum of cognitive
impairments caused by cerebrovascular disease, ranging from mild cognitive impairment to …
impairments caused by cerebrovascular disease, ranging from mild cognitive impairment to …
Recent advances in acetylcholinesterase Inhibitors and Reactivators: an update on the patent literature (2012-2015)
SF McHardy, HYL Wang, SV McCowen… - Expert opinion on …, 2017 - Taylor & Francis
ABSTRACT Introduction: Acetylcholinesterase (AChE) is the major enzyme that hydrolyzes
acetylcholine, a key neurotransmitter for synaptic transmission, into acetic acid and choline …
acetylcholine, a key neurotransmitter for synaptic transmission, into acetic acid and choline …
Praegnatio perturbatio—impact of endocrine-disrupting chemicals
V Padmanabhan, W Song… - Endocrine …, 2021 - academic.oup.com
The burden of adverse pregnancy outcomes such as preterm birth and low birth weight is
considerable across the world. Several risk factors for adverse pregnancy outcomes have …
considerable across the world. Several risk factors for adverse pregnancy outcomes have …
Entomopathogenic fungi based microbial insecticides and their physiological and biochemical effects on Spodoptera frugiperda (JE Smith)
Background 'The fall armyworm, Spodoptera frugiperda', represents a significant threat to
maize production, a major staple crop in Asian countries. Methods In pursuit of more …
maize production, a major staple crop in Asian countries. Methods In pursuit of more …
Recent advances in enzyme inhibition based-electrochemical biosensors for pharmaceutical and environmental analysis
J Li, H Chang, N Zhang, Y He, D Zhang, B Liu, Y Fang - Talanta, 2023 - Elsevier
Enzymes are biological catalysts that facilitate a diverse range of biochemical reactions in a
highly specific and efficient manner. The development of inhibitors of several clinically …
highly specific and efficient manner. The development of inhibitors of several clinically …
Evaluation of apoptosis, oxidative stress responses, AChE activity and body malformations in zebrafish (Danio rerio) embryos exposed to deltamethrin
V Parlak - Chemosphere, 2018 - Elsevier
In this study, we observed the zebrafish embryo/larvae (Danio rerio) exposed to
Deltamethrin (DM) used as pesticide in agricultural fields. We determined respectively …
Deltamethrin (DM) used as pesticide in agricultural fields. We determined respectively …