In the present work, we report compilation and analysis of 245 drugs, including small and
macromolecules approved by the US FDA from 2015 until June 2020. Nearly 29% of the …

Fruits are the seed-bearing product of plants and have considerable nutritional importance
in the human diet. The consumption of fruits is among the dietary strategies recommended …

Constipation is one of the major gastrointestinal disorders diagnosed in clinical practice in
Western countries. Almost 20% of population suffer from this disorder, which means …

Chronic constipation is a common gastrointestinal disorder, with a worldwide incidence of
14–30%. It negatively affects quality of life and is associated with a considerable economic …

Kiwi berry (Actinidia arguta) is beneficial for relieving constipation, but the mechanism of
easing constipation is still unknown. The alleviating effects of kiwi berry polysaccharide and …

The pathogenesis of ulcerative colitis (UC) is complicated with impaired intestinal epithelial
barrier and imbalanced gut microbiota. Both selenium and probiotics have shown effects in …

Refractory constipation is the most severe form of constipation, and its etiology remains
unknown. The symptoms of constipation occur repeatedly, which brings great pain to the …

Constipation, one of the most common prodromal non-motor symptoms of Parkinson's
disease (PD), usually occurs several years earlier than the onset of motor symptoms …

(1) Background: Our previous study found that the dietary fiber supplement in patients with
hypertension increased SCFA-producers, Bififidobacterium and Spirillum in the gut …

To explore mechanism of intestinal flora dysregulation promoting constipation, 60 specific
pathogen-free (SPF) mice were used as research objects and were treated with constipation …