Pathogenesis of pituitary tumors

S Melmed - Nature Reviews Endocrinology, 2011 - nature.com
Pituitary adenomas may hypersecrete hormones (including prolactin, growth hormone and
adrenocorticotropic hormone, and rarely follicle-stimulating hormone, luteinizing hormone or …

Molecular physiology of pituitary development: signaling and transcriptional networks

X Zhu, AS Gleiberman… - Physiological …, 2007 - journals.physiology.org
The pituitary gland is a central endocrine organ regulating basic physiological functions,
including growth, the stress response, reproduction, metabolic homeostasis, and lactation …

Opposing LSD1 complexes function in developmental gene activation and repression programmes

J Wang, K Scully, X Zhu, L Cai, J Zhang… - Nature, 2007 - nature.com
Precise control of transcriptional programmes underlying metazoan development is
modulated by enzymatically active co-regulatory complexes, coupled with epigenetic …

[HTML][HTML] Cellular and molecular specificity of pituitary gland physiology

C Perez-Castro, U Renner, MR Haedo… - Physiological …, 2012 - journals.physiology.org
The anterior pituitary gland has the ability to respond to complex signals derived from central
and peripheral systems. Perception of these signals and their integration are mediated by …

Genetic control of growth

PE Mullis - European journal of endocrinology, 2005 - academic.oup.com
The application of the powerful tool molecular biology has made it possible to ask questions
not only about hormone production and action but also to characterize many of the receptor …

Hes1 and Hes5 Control the Progenitor Pool, Intermediate Lobe Specification, and Posterior Lobe Formation in the Pituitary Development

A Kita, I Imayoshi, M Hojo, M Kitagawa… - Molecular …, 2007 - academic.oup.com
The pituitary gland is composed of two distinct entities: the adenohypophysis, including the
anterior and intermediate lobes, and the neurohypophysis, known as the posterior lobe. This …

A Novel LHX3 Mutation Presenting as Combined Pituitary Hormonal Deficiency

APS Bhangoo, CS Hunter, JJ Savage… - The Journal of …, 2006 - academic.oup.com
Context: LHX3 encodes LIM homeodomain class transcription factors with important roles in
pituitary and nervous system development. The only previous report of LHX3 mutations …

Genetic control of pituitary development and hypopituitarism

X Zhu, CR Lin, GG Prefontaine, J Tollkuhn… - Current opinion in …, 2005 - Elsevier
The pituitary gland functions as a relay between the hypothalamus and peripheral target
organs that regulate basic physiological functions, including growth, the stress response …

Transcriptional control of precursor proliferation in the early phases of pituitary development

X Zhu, MG Rosenfeld - Current opinion in genetics & development, 2004 - Elsevier
The anterior pituitary is derived from Rathke's pouch arising from the oral ectoderm. The
initial apparently uniform precursor cells proliferate and differentiate into six different cell …

[HTML][HTML] Eya1 is required for lineage-specific differentiation, but not for cell survival in the zebrafish adenohypophysis

G Nica, W Herzog, C Sonntag, M Nowak… - Developmental …, 2006 - Elsevier
The homeodomain transcription factor Six1 and its modulator, the protein phosphatase
Eya1, cooperate to promote cell differentiation and survival during mouse organ …