[HTML][HTML] Genetic evidence for the causal effects of C–reactive protein on self-reported habitual sleep duration

O Iakunchykova, M Pan, IK Amlien, JM Roe… - Brain, behavior, & …, 2024 - Elsevier
Inflammatory responses to acute stimuli are proposed to regulate sleep, but the relationship
between chronic inflammation and habitual sleep duration is elusive. Here, we study this …

[HTML][HTML] Migraine and gastroesophageal reflux disease: Disentangling the complex connection with depression as a mediator

Z Shen, Y Bian, Y Huang, W Zhou, H Chen, X Zhou… - Plos one, 2024 - journals.plos.org
Objective Gastroesophageal reflux disease (GERD) and migraine are public health
concerns worldwide. No observational study has conclusively elucidated the causal …

[HTML][HTML] Genetically predicted processed meat, red meat intake, and risk of mental disorders: A multivariable Mendelian randomization analysis

M Liu, W Wang, Y Chen, M Guo, Y Wei, S Yang… - Journal of Affective …, 2024 - Elsevier
Background Previous observational studies have highlighted potential links between the
consumption of processed meat and red meat (such as pork, mutton, and beef intake) and …

Causal Links Between Systemic Disorders and Keratoconus in European Population

X Chen, L Chen - American Journal of Ophthalmology, 2024 - Elsevier
Purpose To establish the presence of a causal linkage between prevalent systemic diseases
and keratoconus (KC). Design Mendelian randomization (MR) analysis. Methods After an …

Genetic predictors of traits in elderly subjects: risk of survival bias and reverse causation

S Burgess, A Zhou - European Heart Journal, 2024 - academic.oup.com
Schematic diagram indicating potential biasing causal pathways. For a valid Mendelian
randomization analysis, all causal pathways from the genetic variants to the outcome must …

COVID-19 and retinal layer thickness: A bidirectional Mendelian randomization study

K Zhao, X Xiang, Z Zheng, Q Zhang, B Gu… - Multiple Sclerosis and …, 2024 - Elsevier
Background Observational studies have reported that COVID-19 is associated with
alterations in retinal layer thickness, including changes in the ganglion cell inner plexiform …