Most organisms display endogenously produced∼ 24-hour fluctuations in physiology and
behavior, termed circadian rhythms. Circadian rhythms are driven by a transcriptional …

Cushing syndrome results from supraphysiological exposure to glucocorticoids and is
associated with significant morbidity and mortality. The pathogenesis includes …

Background: Stress is associated with an increased incidence of cardiovascular disease.
The impact of chronic stress on cardiovascular risk has been studied by measuring cortisol …

Objective In this study, we aim to assess the long-term survival and causes of death in a
retrospective cohort study on patients with all aetiologies of endogenous Cushing's …

Telomere length (TL) has long been associated with aging, as telomeres serve as protective
caps of chromosomes, and are thus deeply involved in the preservation of genome integrity …

Erectile dysfunction is highly prevalent, affecting up to half of men in their 50–70s, and has
been variably associated to a variety of causes including unhealthy lifestyles, such as …

Measurement of Health-Related Quality of Life (HRQoL) is emerging as an important clinical
endpoint which complements diagnostic workup and contributes to place patients at the …

Cushing's disease is a rare chronic disease caused by a pituitary adenoma, which leads to
excess secretion of adrenocorticotropic hormone (ACTH). The over-production of ACTH …

Abstract Context Pituitary neuroendocrine tumors (PitNETs) are a commonly underestimated
pathology in terms of incidence and associated morbimortality. Currently, an appreciable …

In recent years, the usefulness of dual-energy X-ray absorptiometry (DXA) as a valuable
complementary method of assessing the content and distribution of adipose and lean tissue …