Neural tube defects are severe congenital malformations affecting around one in every 1000
pregnancies. An innovation in clinical management has come from the finding that closure of …

Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth
defects of the central nervous system that originate during embryonic development when the …

The clinical significance of periconceptional folic acid supplementation (FAS) in the
prevention of neonatal neural tube defects (NTDs) has been recognized for decades …

At a time when complex diseases affect globally 280 million people and claim 14 million
lives every year, there is an urgent need to rapidly increase our knowledge into their …

Neural tube defects (NTDs) are a group of severe congenital malformations, induced by the
combined effects of genes and the environment. The most valuable finding so far has been …

Neural tube defects (NTDs) are a broad class of congenital birth defects that result from the
failure of neural tube closure during neurulation. Folic acid supplementation has been …

Neural tube defects (NTDs) consist of severe structural malformations of the brain and spinal
cord and are the second most common structural birth defect in humans, accounting for …

Background While there is strong evidence that genetic risk factors play an important role in
the etiologies of structural birth defects, compared to other diseases, there have been …

Neural tube defects (NTDs) occur secondary to failed closure of the neural tube between the
third and fourth weeks of gestation. The worldwide incidence ranges from 0.3 to 200 per …

Background Neural tube defects (NTDs) is the most common birth defect of the central
nervous system (CNS) which causes the death of almost 88,000 people every year around …