This manuscript reviews the clinical evidence regarding single-dose intravenous (IV)
administration of the novel glutamatergic modulator racemic (R, S)-ketamine (hereafter …

Ketamine, an N-methyl-D-aspartate receptor antagonist, is widely known as a dissociative
anesthetic and phencyclidine derivative. Due to an undesirable adverse event profile when …

Abstract Lower Urinary Tract Symptoms (LUTS) are frequently present in the general
population as patients age with approximately a third of individuals experiencing LUTS …

Mirtazapine belongs to the category of antidepressants clinically used mainly in major
depressive disorder but also used in obsessive-compulsive disorders, generalized anxiety …

Central post-stroke pain is a chronic neuropathic pain syndrome following a cerebrovascular
accident. The development of central post-stroke pain is estimated to occur in 8 to 55% of …

Abstract Purpose of Review Postoperative pain (POP) is among the most unpleasant
experiences that patients face after surgery. Interest in and use of N-methyl-D-aspartate …

Laparoscopic cholecystectomy is widely performed because it results in a relatively easier
pain management and shorter hospital stay. Although postoperative pain following …

Background The use of induction agents for rapid sequence intubation (RSI) has been
associated with hypotension in critically ill patients. Choice of induction agent may be …

Various clinical reports indicate prolonged exposure to general anesthetic-induced
neurotoxicity (in vitro and in vivo). Behavior changes (memory and cognition) are …

Ketamine and its enantiomer S‐ketamine (esketamine) are known to produce rapid‐onset
antidepressant effects in major depression. Intranasal esketamine has recently come onto …