Baicalin mediated regulation of key signaling pathways in cancer
Baicalin has been widely investigated against different types of malignancies both at the
cellular and molecular levels over the past few years. Due to its remarkable anti-proliferative …
cellular and molecular levels over the past few years. Due to its remarkable anti-proliferative …
Doxorubicin induces an extensive transcriptional and metabolic rewiring in yeast cells
H Taymaz-Nikerel, ME Karabekmez, S Eraslan… - Scientific reports, 2018 - nature.com
Doxorubicin is one of the most effective chemotherapy drugs used against solid tumors in
the treatment of several cancer types. Two different mechanisms,(i) intercalation of …
the treatment of several cancer types. Two different mechanisms,(i) intercalation of …
[HTML][HTML] Roads to melanoma: Key pathways and emerging players in melanoma progression and oncogenic signaling
J Paluncic, Z Kovacevic, PJ Jansson… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Melanoma has markedly increased worldwide during the past several decades in the
Caucasian population and is responsible for 80% of skin cancer deaths. Considering that …
Caucasian population and is responsible for 80% of skin cancer deaths. Considering that …
Oncopreventive and oncotherapeutic potential of licorice triterpenoid compound glycyrrhizin and its derivatives: Molecular insights
R Jain, MA Hussein, S Pierce, C Martens… - Pharmacological …, 2022 - Elsevier
Licorice (Glycyrrhiza glabra) is a well-known natural herb used to treat different ailments
since ancient times. Glycyrrhizin (GL), which is the primary triterpenoid compound of licorice …
since ancient times. Glycyrrhizin (GL), which is the primary triterpenoid compound of licorice …
Curcumin: modulator of key molecular signaling pathways in hormone-independent breast cancer
R Farghadani, R Naidu - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer remains the most commonly diagnosed cancer and the
leading cause of cancer death among females worldwide. It is a highly heterogeneous …
leading cause of cancer death among females worldwide. It is a highly heterogeneous …
Unraveling the wide spectrum of melanoma biomarkers
A Revythis, S Shah, M Kutka, M Moschetta, MA Ozturk… - Diagnostics, 2021 - mdpi.com
The use of biomarkers in medicine has become essential in clinical practice in order to help
with diagnosis, prognostication and prediction of treatment response. Since Alexander …
with diagnosis, prognostication and prediction of treatment response. Since Alexander …
The functions and molecular mechanisms of Tribbles homolog 3 (TRIB3) implicated in the pathophysiology of cancer
A Arif, AA Alameri, UB Tariq, SA Ansari, HI Sakr… - International …, 2023 - Elsevier
Currently, cancer ranks as the second leading cause of death worldwide, and at the same
time, the burden of cancer continues to increase. The underlying molecular pathways …
time, the burden of cancer continues to increase. The underlying molecular pathways …
Therapeutic strategies involving survivin inhibition in cancer
D Martínez‐García, N Manero‐Rupérez… - Medicinal Research …, 2019 - Wiley Online Library
Survivin is a small protein that belongs to the inhibitor of apoptosis protein family. It is
abundantly expressed in tumors compared with adult differentiated tissues, being …
abundantly expressed in tumors compared with adult differentiated tissues, being …
Investigation of antigen-specific T-cell receptor clusters in human cancers
Purpose: Cancer antigen–specific T cells are key components in antitumor immune
response, yet their identification in the tumor microenvironment remains challenging, as …
response, yet their identification in the tumor microenvironment remains challenging, as …
A recent update on small‐molecule kinase inhibitors for targeted cancer therapy and their therapeutic insights from mass spectrometry‐based proteomic analysis
Kinases are key regulatory signalling proteins governing numerous essential biological
processes and cellular functions. Dysregulation of many protein kinases is associated with …
processes and cellular functions. Dysregulation of many protein kinases is associated with …