Background: Some patients with metastatic differentiated thyroid cancer (DTC) lack iodine
avidity and are therefore unsuitable for radioactive iodine (RAI) therapy. Limited experience …

Background USP11 is an ubiquitin-specific protease that plays an important role in tumor
progression via different mechanisms. However, the expression and prognostic significance …

Simple Summary The tumor microenvironment is a complex network comprised of
neoplastic and a variety of immune cells, proteins, and inflammatory mediators. Previous …

Despite advances in diagnostic tools and therapeutic options, treatment resistance remains
a challenge for many cancer patients. Recent studies have found evidence that autophagy …

Epigallocatechin gallate (EGCG) is the main bioactive component of catechins
predominantly present in various types of tea. EGCG is well known for a wide spectrum of …

Primary cilia are microtubule‑based organelles that are expressed on almost all mammalian
cells. It has become apparent that these structures are important signaling hubs that serve …

Phosphoinositides (PI) form just a minor portion of the total phospholipid content in cells but
are significantly involved in cancer development and progression. In several cancer types …

Accumulating evidence has demonstrated that N6-methyladenosine (m6A) plays important
roles in various cancers, making it essential to profile m6A modifications at a transcriptome …

Background A novel type of noncoding RNA, circRNA has been reported to participate in the
occurrence and development of diseases through many mechanisms. The MAPK pathway is …

Nature, a vast reservoir of pharmacologically active molecules, has been most promising
source of drug leads for the cure of various pathological conditions. Formononetin is one of …