Combined methylome, transcriptome and proteome analyses document rapid acclimatization of a bacterium to environmental changes

A Srivastava, J Murugaiyan, JAL Garcia… - Frontiers in …, 2020 - frontiersin.org
Polynucleobacter asymbioticus strain QLW-P1DMWA-1T represents a group of highly
successful heterotrophic ultramicrobacteria that is frequently very abundant (up to 70% of …

Genomic analysis of the regulatory elements and links with intrinsic DNA structural properties in the shrunken genome of Buchnera

L Brinza, F Calevro, H Charles - BMC genomics, 2013 - Springer
Background Buchnera aphidicola is an obligate symbiotic bacterium, associated with most
of the aphididae, whose genome has drastically shrunk during intracellular evolution. Gene …

An integrated transcriptomics–functional genomics approach reveals a small RNA that modulates Bacteroides thetaiotaomicron sensitivity to tetracyclines

D Ryan, E Bornet, G Prezza, SV Alampalli, TF Carvalho… - bioRxiv, 2023 - biorxiv.org
Gene expression plasticity allows bacteria to adapt to diverse environments, tie their
metabolism to available nutrients, and cope with stress. This is particularly relevant in a …

A functional genomics catalogue of activated transcription factors during pathogenesis of pneumococcal disease

LK Mahdi, T Deihimi, F Zamansani, M Fruzangohar… - BMC genomics, 2014 - Springer
Background Streptococcus pneumoniae (the pneumococcus) is the world's foremost
microbial pathogen, killing more people each year than HIV, TB or malaria. The capacity to …

After the fact (or): posttranscriptional gene regulation in enterohemorrhagic Escherichia coli O157: H7

AB Sauder, MM Kendall - Journal of Bacteriology, 2018 - Am Soc Microbiol
To adapt to ever-changing environments, pathogens quickly alter gene expression. This can
occur through transcriptional, posttranscriptional, or posttranslational regulation. Historically …

Pneumococcal metabolic adaptation and colonization are regulated by the two-component regulatory system 08

A Gómez-Mejia, G Gámez, S Hirschmann, V Kluger… - Msphere, 2018 - Am Soc Microbiol
Streptococcus pneumoniae two-component regulatory systems (TCS) enable adaptation
and ensure its maintenance in host environments. This study deciphers the impact of TCS08 …

RNase III and RNase E influence posttranscriptional regulatory networks involved in virulence factor production, metabolism, and regulatory RNA processing in …

G Ifill, T Blimkie, AHY Lee, GA Mackie, Q Chen… - Msphere, 2021 - Am Soc Microbiol
Bordetella pertussis has been shown to encode regulatory RNAs, yet the posttranscriptional
regulatory circuits on which they act remain to be fully elucidated. We generated mutants …

The gene regulatory network of Staphylococcus aureus ST239-SCCmecIII strain Bmb9393 and assessment of genes associated with the biofilm in diverse …

MOC Costa, APB Nascimento, YC Martins… - Frontiers in …, 2023 - frontiersin.org
Introduction Staphylococcus aureus is one of the most prevalent and relevant pathogens
responsible for a wide spectrum of hospital-associated or community-acquired infections. In …

Interplay between copper and zinc homeostasis through the transcriptional regulator Zur in Enterococcus faecalis

M Latorre, M Low, E Gárate, A Reyes-Jara… - Metallomics, 2015 - academic.oup.com
By integrating the microarray expression data and a global E. faecalis transcriptional
network we identified a sub-network activated by zinc and copper. Our analyses indicated …

An iterative, synthetic approach to engineer a high-performance PhoB-specific reporter

JL Stoudenmire, T Essock-Burns… - Applied and …, 2018 - Am Soc Microbiol
Transcriptional reporters are common tools for analyzing either the transcription of a gene of
interest or the activity of a specific transcriptional regulator. Unfortunately, the latter …