Vitamin D is a steroid hormone classically involved in the calcium metabolism and bone
homeostasis. Recently, new and interesting aspects of vitamin D metabolism has been …

Vitamin D has a key role in stimulating calcium absorption from the gut and promoting
skeletal health, as well as many other important physiological functions. Vitamin D is …

1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

Discovered many decades earlier by Mellanby, 1 McCollum and colleagues, 2 Steenbock, 3
and Windaus and colleagues, 4 vitamin D is now known through ensuing research efforts by …

Vitamin D, referring to the two forms, D2 from the diet and D3 primarily derived from
phototransformation in the skin, is a prohormone important in human health. The most …

The interest in vitamin D continues unabated with thousands of publications contributing to a
vast and growing literature each year. It is widely recognized that the vitamin D receptor …

Vitamin D is known not only for its importance for bone health but also for its biologic
activities on many other organ systems. This is due to the presence of the vitamin D receptor …

Rickets is a bone disease associated with abnormal serum calcium and phosphate levels.
The clinical presentation is heterogeneous and depends on the age of onset and …

Bioactivation of vitamin D consists of two sequential hydroxylation steps to produce 1α, 25-
dihydroxyvitamin D3. It is clear that the second or 1α-hydroxylation step is carried out by a …

Background: The Middle East and North Africa (MENA) region registers some of the highest
rates of hypovitaminosis D worldwide. Aim: We systematically reviewed the prevalence of …