Abstract High lipoprotein (a)[Lp (a)] concentrations are one of the most important genetically
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …

Abstract Purpose of Review Epigenetic modifications via DNA methylation have previously
been linked to blood lipid levels, dyslipidemias, and atherosclerosis. The purpose of this …

BACKGROUND: High levels of Lp (a)(lipoprotein (a)) are associated with multiple forms of
cardiovascular disease. Lp (a) consists of an apoB100-containing particle attached to the …

Measurement of Lp (a) in the clinical setting contributes to the assessment of ASCVD risk,
and will become more important with the advent of specific Lp (a)-lowering therapies …

Background Individuals born very low birthweight (VLBW) are at increased risk of impaired
cardiovascular and respiratory function in adulthood. To identify markers to predict future risk …

Abstract Background & Methods In this study, a novel restriction enzyme (RE) digestion-
based droplet digital polymerase chain reaction (ddPCR) assay was designed for …

Array-based EWAS have become an increasingly popular technique to identify population
epigenetic effects, particularly in humans. With the arrival of nonhuman species arrays, such …

ABSTRACT DNA methylation (DNAm) epigenome-wide association studies (EWAS) have
been performed on diverse ethnicities to discover novel biomarkers associated with various …

Aims Cohort studies have demonstrated associations between calcific aortic valve disease
(CAVD) and Lp (a). As Lp (a) is almost entirely genetically determined, in this study, we aim …

Cardiovascular diseases are the leading cause of morbidity and mortality worldwide.
Genome-wide association studies (GWAS) are powerful epidemiological tools to find genes …