Although traditionally seen as regulators of hematopoiesis, colony-stimulating factors (CSFs)
have emerged as important players in the nervous system, both in health and disease. This …

In the management of human immunodeficiency virus (HIV) infection around the world,
chronic complications are becoming a new problem along with the prolonged life …

The accumulation of alpha-synuclein (αSyn) is widely recognized as the main pathological
process in Parkinson's disease (PD). Additionally, neuroinflammation is considered to be …

Peripheral nerve injury is a significant public health challenge, with limited treatment options
and potential lifelong impact on function. More than just an intrinsic part of nerve anatomy …

The pathological mechanism of neuropathic pain is complex, which seriously affects the
physical and mental health of patients, and its treatment is also difficult. The role of G protein …

Molecular and cellular interactions among spinal dorsal horn neurons and microglia, the
resident macrophages of the central nervous system, contribute to the induction and …

The role of microglia in mediating age‐related changes in cognition and hippocampal
synaptic function was examined by microglial depletion and replenishment using PLX3397 …

Peripheral nerve injuries remain challenging to treat despite extensive research on
reparative processes at the injury site. Recent studies have emphasized the importance of …

A significant portion of individuals living with traumatic spinal cord injury (SCI) experiences
some degree of debilitating neuropathic pain (NP). This pain remains largely intractable in a …

Background Previous studies have proved that peripheral nerve injury is involved in the
pathogenesis of neuropathic pain (NP). The peripheral nerve injury primes spinal M1 …