The LIN28/let-7 pathway in cancer
Among all tumor suppressor microRNAs, reduced let-7 expression occurs most frequently in
cancer and typically correlates with poor prognosis. Activation of either LIN28A or LIN28B …
cancer and typically correlates with poor prognosis. Activation of either LIN28A or LIN28B …
miRNAs and ovarian cancer: An overview
B Deb, A Uddin, S Chakraborty - Journal of cellular physiology, 2018 - Wiley Online Library
Ovarian cancer (OC) is the sixth most common cancer in women globally. However, even
with the advances in detection and therapeutics it still represents the most dangerous …
with the advances in detection and therapeutics it still represents the most dangerous …
Five freely circulating miRNAs and bone tissue miRNAs are associated with osteoporotic fractures
C Seeliger, K Karpinski, AT Haug… - Journal of Bone and …, 2014 - academic.oup.com
Osteoporosis as a systemic skeletal disorder is characterized by increased bone fragility and
the risk of fractures. According to the World Health Organization, osteoporosis is one of the …
the risk of fractures. According to the World Health Organization, osteoporosis is one of the …
Molecular mechanisms of drug resistance in ovarian cancer
L Norouzi‐Barough, MR Sarookhani… - Journal of cellular …, 2018 - Wiley Online Library
Ovarian cancer is the most lethal malignancy among the gynecological cancers, with a 5‐
year survival rate, mainly due to being diagnosed at advanced stages, recurrence and …
year survival rate, mainly due to being diagnosed at advanced stages, recurrence and …
microRNA-184 in the landscape of human malignancies: a review to roles and clinical significance
MicroRNAs (miRNAs) are a class of non-coding RNAs (ncRNAs) with a short length of 19–
22 nucleotides. miRNAs are posttranscriptional regulators of gene expression involved in …
22 nucleotides. miRNAs are posttranscriptional regulators of gene expression involved in …
Discovery of multi-dimensional modules by integrative analysis of cancer genomic data
Recent technology has made it possible to simultaneously perform multi-platform genomic
profiling (eg DNA methylation (DM) and gene expression (GE)) of biological samples …
profiling (eg DNA methylation (DM) and gene expression (GE)) of biological samples …
microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial–mesenchymal transition
A Parikh, C Lee, P Joseph, S Marchini… - Nature …, 2014 - nature.com
Ovarian cancer is a leading cause of cancer deaths among women. Effective targets to treat
advanced epithelial ovarian cancer (EOC) and biomarkers to predict treatment response are …
advanced epithelial ovarian cancer (EOC) and biomarkers to predict treatment response are …
Plasma microRNAs as novel biomarkers for endometriosis and endometriosis-associated ovarian cancer
Purpose: Endometriosis, a largely benign, chronic inflammatory disease, is an independent
risk factor for endometrioid and clear cell epithelial ovarian tumors. We aimed to identify …
risk factor for endometrioid and clear cell epithelial ovarian tumors. We aimed to identify …
A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis
A Vecchione, B Belletti, F Lovat… - Proceedings of the …, 2013 - National Acad Sciences
Epithelial ovarian cancer is the most lethal gynecologic malignancy; it is highly aggressive
and causes almost 125,000 deaths yearly. Despite advances in detection and cytotoxic …
and causes almost 125,000 deaths yearly. Despite advances in detection and cytotoxic …
Circulating biomarkers for detection of ovarian cancer and predicting cancer outcomes
I Shapira, M Oswald, J Lovecchio, H Khalili… - British journal of …, 2014 - nature.com
Background: Securing a diagnosis of ovarian cancer and establishing means to predict
outcomes to therapeutics remain formidable clinical challenges. Early diagnosis is …
outcomes to therapeutics remain formidable clinical challenges. Early diagnosis is …