Emerging roles for human glycolipid transfer protein superfamily members in the regulation of autophagy, inflammation, and cell death
Glycolipid transfer proteins (GLTPs) were first identified over three decades ago as~ 24kDa,
soluble, amphitropic proteins that specifically accelerate the intermembrane transfer of …
soluble, amphitropic proteins that specifically accelerate the intermembrane transfer of …
[HTML][HTML] Sphingolipid-transporting proteins as cancer therapeutic targets
D Samaha, HH Hamdo, M Wilde, K Prause… - International Journal of …, 2019 - mdpi.com
The understanding of the role of sphingolipid metabolism in cancer has tremendously
increased in the past ten years. Many tumors are characterized by imbalances in …
increased in the past ten years. Many tumors are characterized by imbalances in …
[HTML][HTML] Structural basis of phosphatidylcholine recognition by the C2–domain of cytosolic phospholipase A2α
Ca2+-stimulated translocation of cytosolic phospholipase A2α (cPLA2α) to the Golgi induces
arachidonic acid production, the rate-limiting step in pro-inflammatory eicosanoid synthesis …
arachidonic acid production, the rate-limiting step in pro-inflammatory eicosanoid synthesis …
Ceramide-1-phosphate and its transfer proteins in eukaryotes
Y Zhang, X Zhang, M Lu, X Zou - Chemistry and Physics of Lipids, 2021 - Elsevier
Abstract Ceramide-1-phosphate (C1P) is a bioactive phosphorylated sphingolipid (SL),
produced through the direct phosphorylation of ceramide by ceramide kinase. It plays …
produced through the direct phosphorylation of ceramide by ceramide kinase. It plays …
[HTML][HTML] Ceramide-1-phosphate transfer protein (CPTP) regulation by phosphoinositides
YG Gao, X Zhai, IA Boldyrev, JG Molotkovsky… - Journal of Biological …, 2021 - ASBMB
Ceramide-1-phosphate transfer proteins (CPTPs) are members of the glycolipid transfer
protein (GLTP) superfamily that shuttle ceramide-1-phosphate (C1P) between membranes …
protein (GLTP) superfamily that shuttle ceramide-1-phosphate (C1P) between membranes …
[HTML][HTML] Ceramide-1-phosphate transfer protein promotes sphingolipid reorientation needed for binding during membrane interaction
Lipid transfer proteins acquire and release their lipid cargoes by interacting transiently with
source and destination biomembranes. In the GlycoLipid Transfer Protein (GLTP) …
source and destination biomembranes. In the GlycoLipid Transfer Protein (GLTP) …
Role of Gltp in Maturation of Oligodendrocytes Under the Regulation of Nkx2.2
C Zhang, Z Chen, D Zhang, X Wang, M Qiu… - Molecular …, 2023 - Springer
Myelin, a lipid-enriched multi-layer membrane structure, allows for rapid long-distance
saltatory conduction of neuronal impulses. Although glycolipids are the predominant types of …
saltatory conduction of neuronal impulses. Although glycolipids are the predominant types of …
Measuring lipid transfer protein activity using Bicelle-Dilution model membranes
YG Gao, LT My Le, X Zhai, IA Boldyrev… - Analytical …, 2020 - ACS Publications
In vitro assessment of lipid intermembrane transfer activity by cellular proteins typically
involves measurement of either radiolabeled or fluorescently labeled lipid trafficking …
involves measurement of either radiolabeled or fluorescently labeled lipid trafficking …
[PDF][PDF] 基于生物信息学方法的人类GLTP 在胰腺腺癌发生发展中的作用及其表观遗传调控机制分析
马梅燕， 冀慎英， 张湘豫， 卢梦云， 邹先琼 - 激光生物学报, 2021 - jgsw.hunnu.edu.cn
通过生物信息学方法分析人类糖脂转运蛋白(GLTP) 的基因在肿瘤发生发展中的作用及其表观
遗传调控机制. 利用UCSC Genome Browser, EMBOSS 及GEPIA 等在线生物信息学分析工具 …
遗传调控机制. 利用UCSC Genome Browser, EMBOSS 及GEPIA 等在线生物信息学分析工具 …
In silico docking of vitamin E isomers on transport proteins
NS Zulkiflee, SA Awang, WX Ming… - … -Aided Drug Design, 2020 - ingentaconnect.com
Background: Vitamin E is comprised of α, β, γ and δ-tocopherols (Ts) and α, β, γ and δ-
tocotrienols (T3s). Vitamin E has neuroprotective antioxidant, anti-cancer, and cholesterol …
tocotrienols (T3s). Vitamin E has neuroprotective antioxidant, anti-cancer, and cholesterol …