Background Fibromyalgia is a centralized multidimensional chronic pain syndrome, but its
pathophysiology is not fully understood. Methods We applied 3D magnetic resonance …

Tapentadol and oxycodone are commonly used analgesics. Preclinical studies have shown
that oxycodone modulates brain metabolites related to opioid pathways, whereas tapentadol …

Crohn's disease (CD) is a chronic and relapsing inflammatory bowel disorder that has been
shown to generate neurological impairments, which has the potential to signify disease …

This article reviews the main literature published between April 2018 and March 2019 in the
field of the microbiota-gut-brain axis focusing on gastrointestinal inflammation and …

Neurotransmitters such as serotonin, norepinephrine (NE), dopamine (DA), gamma-
aminobutyric acid (GABA), and histamine play a crucial role in normal human physiology …

There is mounting evidence of an associative link between inflammatory bowel disease
(IBD) and clinical depression. In the first major treatise on the eponymous disease, Burrill …

This thesis describes how induced gut inflammation induces brain inflammation via the brain-
gut axis. It further shows that mice with elevated gut inflammation display post-shock …

炎性肠病是一类由多种病因引起的肠道慢性及复发性炎症性疾病, 具有终身复发的倾向.
除了已知的关节炎, 虹膜炎等肠道外症状, 有研究指出, 炎性肠病患者还存在神经系统受累 …

Bakgrund: Smärta definieras som en subjektiv upplevelse där upplevelsen till viss del
formas i hjärnan genom komplexa processer. Långvarig stress har visat sig leda till …

The International Association for the Study of Pain (IASP) defines pain as “an unpleasant
sensory or emotional experience associated with actual or potential tissue damage or …