The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …

Since the dawn of civilization, it has been understood that pathogenic microorganisms
cause infectious conditions in humans, which at times, may prove fatal. Among the different …

Fungal biofilm infections have become increasingly recognised as a significant clinical
problem. One of the major reasons behind this is the impact that these have upon treatment …

Biofilms comprising aggregates of microorganisms or multicellular communities have been a
major issue as they cause resistance against antimicrobial agents and biofouling. To date …

The emergence of new fungal pathogens makes the development of new antifungal drugs a
medical imperative that in recent years motivates the talents of numerous investigators …

Aspergillus fumigatus is the most important airborne fungal pathogen, causing severe
infections with invasive growth in immunocompromised patients. The fungal cell wall (CW) …

Fungal biofilms are communities of adherent cells surrounded by an extracellular matrix.
These biofilms are commonly found during infection caused by a variety of fungal …

A biofilm is an assemblage, aggregation, or community of microbial cells bounded by a
polymeric matrix comprising polysaccharides that are associated with an inert or biotic …

While Aspergillus spp. remain the major cause of invasive mold infections in hematologic
cancer patients and transplant recipients, other opportunistic molds, such as Mucorales …

A wide variety of fungi have demonstrated the ability to colonize surfaces and form biofilms.
Most studies on fungal biofilms have focused on Candida albicans and more recently …