Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response

M Ashrafizadeh, CD Mohan… - Medicinal research …, 2023 - Wiley Online Library
Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …

[HTML][HTML] The role of the tumor microbiome in tumor development and its treatment

Y Chen, FH Wu, PQ Wu, HY Xing, T Ma - Frontiers in Immunology, 2022 - frontiersin.org
Commensal bacteria and other microorganisms that reside in the human body are closely
associated with the development and treatment of cancers. Recently, tumor microbiome …

[HTML][HTML] The interplay between Helicobacter pylori and the gut microbiota: An emerging driver influencing the immune system homeostasis and gastric …

F Fakharian, B Asgari, A Nabavi-Rad… - Frontiers in cellular …, 2022 - frontiersin.org
The human gut microbiota are critical for preserving the health status because they are
required for digestion and nutrient acquisition, the development of the immune system, and …

[HTML][HTML] The role of the gut microbiota in gastric cancer: the immunoregulation and immunotherapy

M Wang, G Yang, Y Tian, Q Zhang, Z Liu… - Frontiers in …, 2023 - frontiersin.org
Gastric cancer (GC) is one of the most common cancers, leading to the deaths of millions of
people worldwide. Therefore, early detection and effective therapeutic strategies are of great …

[HTML][HTML] Tumor-infiltrating mast cells stimulate ICOS+ regulatory T cells through an IL-33 and IL-2 axis to promote gastric cancer progression

Y Lv, W Tian, Y Teng, P Wang, Y Zhao, Z Li… - Journal of Advanced …, 2024 - Elsevier
Introduction In solid tumors, regulatory T cell (Treg) and mast cell perform different roles
depending on the microenvironment. Nevertheless, mast cell and Treg-mediated …

[HTML][HTML] Inflammatory microenvironment in gastric premalignant lesions: implication and application

S Zhang, Y Shen, H Liu, D Zhu, J Fang, H Pan… - Frontiers in …, 2023 - frontiersin.org
Gastric precancerous lesions (GPL) are a major health concern worldwide due to their
potential to progress to gastric cancer (GC). Understanding the mechanism underlying the …

[HTML][HTML] Bacteria-based immunotherapy for cancer: a systematic review of preclinical studies

M Zhou, Y Tang, W Xu, X Hao, Y Li, S Huang… - Frontiers in …, 2023 - frontiersin.org
Immunotherapy has been emerging as a powerful strategy for cancer management.
Recently, accumulating evidence has demonstrated that bacteria-based immunotherapy …

Diversification and deleterious role of microbiome in gastric cancer

I Chattopadhyay, R Gundamaraju, A Rajeev - Cancer Reports, 2023 - Wiley Online Library
Gut microbiota dictates the fate of several diseases, including cancer. Most gastric cancers
(GC) belong to gastric adenocarcinomas (GAC). Helicobacter pylori colonizes the gastric …

[HTML][HTML] Immunomodulation by gut microbiome on gastrointestinal cancers: focusing on colorectal cancer

RK Al-Ishaq, L Koklesova, P Kubatka, D Büsselberg - Cancers, 2022 - mdpi.com
Simple Summary A symbiotic relationship with the host gut microbiome influences the
immune system's development, functions, and activities. In the mucosa, the gut microbiome …

[HTML][HTML] Effective regulation of gut microbiota with probiotics and prebiotics may prevent or alleviate COVID-19 through the gut-lung axis

L Xu, CS Yang, Y Liu, X Zhang - Frontiers in Pharmacology, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) can disrupt the gut microbiota balance, and patients
usually have intestinal disorders. The intestine is the largest immune organ of the human …