Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic

B Blasco, D Leroy, DA Fidock - Nature medicine, 2017 - nature.com
The global adoption of artemisinin-based combination therapies (ACTs) in the early 2000s
heralded a new era in effectively treating drug-resistant Plasmodium falciparum malaria …

Antimalarial drug resistance in Africa: the calm before the storm?

MD Conrad, PJ Rosenthal - The Lancet Infectious Diseases, 2019 - thelancet.com
Antimalarial drug resistance, in particular resistance to Plasmodium falciparum, challenges
the treatment and control of malaria. In this Review, we summarise evolving patterns of …

[HTML][HTML] Malaria in 2022: Increasing challenges, cautious optimism

P Jagannathan, A Kakuru - Nature communications, 2022 - nature.com
Malaria cases and deaths remain unacceptably high and are resurgent in several settings,
though recent developments inspire optimism. This includes the approval of the world's first …

Malaria during pregnancy

M Fried, PE Duffy - Cold Spring Harbor …, 2017 - perspectivesinmedicine.cshlp.org
One hundred and twenty-five million women in malaria-endemic areas become pregnant
each year (see Dellicour et al. PLoS Med 7: e1000221 [2010]) and require protection from …

[HTML][HTML] Effect of monthly intermittent preventive treatment with dihydroartemisinin–piperaquine with and without azithromycin versus monthly sulfadoxine …

M Madanitsa, HC Barsosio, DTR Minja, G Mtove… - The Lancet, 2023 - thelancet.com
Background Intermittent preventive treatment in pregnancy (IPTp) with dihydroartemisinin–
piperaquine is more effective than IPTp with sulfadoxine–pyrimethamine at reducing malaria …

Prevention of malaria in pregnancy

M Desai, J Hill, S Fernandes, P Walker… - The Lancet infectious …, 2018 - thelancet.com
Malaria remains one of the most preventable causes of adverse birth outcomes. Intermittent
preventive treatment in pregnancy (IPTp) with sulfadoxine–pyrimethamine is used to prevent …

[HTML][HTML] Plasmodium falciparum resistance to ACTs: Emergence, mechanisms, and outlook

FA Siddiqui, X Liang, L Cui - … Journal for Parasitology: Drugs and Drug …, 2021 - Elsevier
Emergence and spread of resistance in Plasmodium falciparum to the frontline treatment
artemisinin-based combination therapies (ACTs) in the epicenter of multidrug resistance of …

[HTML][HTML] Resistance to artemisinin combination therapies (ACTs): do not forget the partner drug!

C Nsanzabana - Tropical medicine and infectious disease, 2019 - mdpi.com
Artemisinin-based combination therapies (ACTs) have become the mainstay for malaria
treatment in almost all malaria endemic settings. Artemisinin derivatives are highly potent …

An overview of malaria in pregnancy

M Bauserman, AL Conroy, K North, J Patterson… - Seminars in …, 2019 - Elsevier
One hundred twenty-five million pregnant women are at risk for contracting malaria, a
preventable cause of maternal and infant morbidity and death. Malaria parasites contribute …

[HTML][HTML] Quantification of the association between malaria in pregnancy and stillbirth: a systematic review and meta-analysis

KA Moore, JA Simpson, MJL Scoullar… - The Lancet Global …, 2017 - thelancet.com
Background 2· 6 million stillbirths occur annually worldwide. The association between
malaria in pregnancy and stillbirth has yet to be comprehensively quantified. We aimed to …