Hot-melt extrusion: from theory to application in pharmaceutical formulation—where are we now?

H Patil, SK Vemula, S Narala, P Lakkala… - AAPS …, 2024 - Springer
Hot-melt extrusion (HME) is a globally recognized, robust, effective technology that
enhances the bioavailability of poorly soluble active pharmaceutical ingredients and offers …

A review of hot melt extrusion technology: advantages, applications, key factors and future prospects

X Li, X Hong, S Shuai, X Han, C Li, H Zhang… - Journal of Drug Delivery …, 2024 - Elsevier
After decades of development, hot melt extrusion (HME) technology has matured as a well-
established pharmaceutical methodology. Through the process of extruding both drug and …

Cyclodextrin in drug delivery: Exploring scaffolds, properties, and cutting-edge applications

P Singh, R Mahar - International Journal of Pharmaceutics, 2024 - Elsevier
Cyclodextrins (CDs) are unique cyclic compounds that can form inclusion complexes via
host–guest complexation with a wide range of molecules, thereby altering their …

Fabrication of suppository shells via hot-melt extrusion paired with fused deposition modeling 3D printing techniques

P Zhang, H Wang, S Chung, J Li, SK Vemula… - Journal of Drug Delivery …, 2024 - Elsevier
Abstract Three-dimensional (3D) printing is a potential technique for developing
personalized medicines. Among its applications, mold manufacturing in industrial 3D …

Advancements of hot-melt extrusion technology to address unmet patient needs and pharmaceutical quality aspects

C Park, VS Renuka, BJ Lee, I de la Peña… - Journal of Pharmaceutical …, 2024 - Springer
Background Hot-melt extrusion (HME) significantly affects pharmaceutical manufacturing by
enhancing drug solubility and bioavailability. Advancements in HME technology to produce …

[HTML][HTML] Adapting the process conditions and performance in planetary roller melt granulation (PRMG) via the planetary spindle number

T Lang, J Bartsch - Powder Technology, 2024 - Elsevier
Continuous melt granulation with a planetary roller granulator is a new continuous method
based on the orbital motion of planetary spindles driven by a rotating central spindle in a …

A New Frontier in Hypertension Management: Formulating and Characterizing Subcutaneous Implants using Hot Melt Extrusion

K Chitnis, N Narala, S Narala, SR Munnangi… - 2023 - preprints.org
Hypertension (HTN) is the foremost contributor to cardiovascular diseases (CVD), which
remain a leading cause of death. However, adherence to the properly prescribed dosage …

[PDF][PDF] Research News, Publications, 2021, Volume 3

S Majumdar - 2021 - egrove.olemiss.edu
22. De La Cruz LK, Yang X, Menshikh A, Brewer M, Lu W, Wang M, Wang S, Ji X, Cachuela
A, Yang H, Gallo D, Tan C, Otterbein L, de Caestecker M, Wang B. Adapting decarbonylation …