Counteracting Immunosenescence—Which Therapeutic Strategies Are Promising?
C Hieber, S Grabbe, M Bros - Biomolecules, 2023 - mdpi.com
Aging attenuates the overall responsiveness of the immune system to eradicate pathogens.
The increased production of pro-inflammatory cytokines by innate immune cells under basal …
The increased production of pro-inflammatory cytokines by innate immune cells under basal …
Integrative network-based analysis on multiple Gene Expression Omnibus datasets identifies novel immune molecular markers implicated in non-alcoholic …
J Zhang, Y Shen, X Chen, M Jiang, F Yuan… - Frontiers in …, 2023 - frontiersin.org
Introduction Non-alcoholic steatohepatitis (NASH), an advanced subtype of non-alcoholic
fatty liver disease (NAFLD), has becoming the most important aetiology for end-stage liver …
fatty liver disease (NAFLD), has becoming the most important aetiology for end-stage liver …
Blood transcriptome analysis revealed the crosstalk between COVID-19 and HIV
C Yan, Y Niu, X Wang - Frontiers in Immunology, 2022 - frontiersin.org
Background The severe coronavirus disease 2019 (COVID-19) is an infectious disease
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has …
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has …
ILF3 safeguards telomeres from aberrant homologous recombination as a telomeric R-loop reader
C Wang, Y Huang, Y Yang, R Li, Y Li, H Qiu, J Wu… - Protein & …, 2024 - academic.oup.com
Telomeres are specialized structures at the ends of linear chromosomes that protect
genome stability. The telomeric repeat-containing RNA (TERRA) that is transcribed from …
genome stability. The telomeric repeat-containing RNA (TERRA) that is transcribed from …
Prognostic and immunotherapeutic predictive value of interleukin enhancer-binding factor 3 in hepatocellular carcinoma: Integrated bioinformatics and experimental …
J Qiu, X Wu, Y Luo, Y Yao, X Zhang, B Pan, X Wang… - Gene, 2023 - Elsevier
Interleukin enhancer-binding factor 3 (ILF3) as an RNA-binding protein that plays a critical
role in the process of cancer and antiviral responses. However, no researcher has focused …
role in the process of cancer and antiviral responses. However, no researcher has focused …
Annotation of nuclear lncRNAs based on chromatin interactions
The human genome is pervasively transcribed and produces a wide variety of long non-
coding RNAs (lncRNAs), constituting the majority of transcripts across human cell types …
coding RNAs (lncRNAs), constituting the majority of transcripts across human cell types …
Lefamulin Overcomes Acquired Drug Resistance via Regulating Mitochondrial Homeostasis by Targeting ILF3 in Hepatocellular Carcinoma
Y Zheng, S Ye, S Huang, Y Cheng, Y Zhang… - Advanced …, 2024 - Wiley Online Library
Acquired resistance represents a critical clinical challenge to molecular targeted therapies
such as tyrosine kinase inhibitors (TKIs) treatment in hepatocellular carcinoma (HCC) …
such as tyrosine kinase inhibitors (TKIs) treatment in hepatocellular carcinoma (HCC) …
Systematic identification of cis-interacting lncRNAs and their targets
The human genome is pervasively transcribed and produces a wide variety of long non-
coding RNAs (lncRNAs), constituting the majority of transcripts across human cell types …
coding RNAs (lncRNAs), constituting the majority of transcripts across human cell types …
Simvastatin inhibits PD-L1 via ILF3 to enhance CD8+ T cell-mediated ferroptosis in gastric cancer cells
D Sun, X Cui, W Yang, M Wei, Z Yan, M Zhang, Z Wang… - 2024 - researchsquare.com
Background Immunotherapy is vital in the comprehensive treatment of gastric cancer (GC).
However, the prognosis of GC patients remains unfavorable, necessitating to exploration of …
However, the prognosis of GC patients remains unfavorable, necessitating to exploration of …
Genetic overlap between impaired lung function and cardiovascular diseases revealed by a large-scale genome-wide cross-trait analysis
D Wu, J Zhou, M Lyu, Q Zheng, T Wang, Y Huang, L Liu - 2024 - researchsquare.com
Background Increasing evidence have highlighted the phenotypic association between
impaired lung function and cardiovascular diseases (CVD), but underlying shared genetic …
impaired lung function and cardiovascular diseases (CVD), but underlying shared genetic …