Enhanced Factor H Binding to Sialylated Gonococci Is Restricted to the Sialylated Lacto-N-Neotetraose Lipooligosaccharide Species: Implications for Serum …
We isolated serologically identical (by serovar determination and porin variable region [VR]
typing) strains of Neisseria gonorrhoeae from an infected male and two of his monogamous …
typing) strains of Neisseria gonorrhoeae from an infected male and two of his monogamous …
Biochemical characterization of a Neisseria meningitidis polysialyltransferase reveals novel functional motifs in bacterial sialyltransferases
F Freiberger, H Claus, A Günzel… - Molecular …, 2007 - Wiley Online Library
The extracellular polysaccharide capsule is an essential virulence factor of Neisseria
meningitidis, a leading cause of severe bacterial meningitis and sepsis. Serogroup B strains …
meningitidis, a leading cause of severe bacterial meningitis and sepsis. Serogroup B strains …
Role of Complement in Defense of the Middle Ear Revealed by Restoring the Virulence of Nontypeable Haemophilus influenzae siaB Mutants
MA Figueira, S Ram, R Goldstein, DW Hood… - Infection and …, 2007 - Am Soc Microbiol
Nontypeable (NT) Haemophilus influenzae is an important cause of otitis media in children.
We have shown previously that NT H. influenzae mutants defective in their ability to sialylate …
We have shown previously that NT H. influenzae mutants defective in their ability to sialylate …
Phosphoethanolamine residues on the lipid A moiety of Neisseria gonorrhoeae lipooligosaccharide modulate binding of complement inhibitors and resistance to …
LA Lewis, WM Shafer, T Dutta Ray, S Ram… - Infection and …, 2013 - Am Soc Microbiol
Loss of phosphoethanolamine (PEA) from the lipid A of gonococcal strain FA19 results in
increased sensitivity to killing by the classical pathway of complement. Here we demonstrate …
increased sensitivity to killing by the classical pathway of complement. Here we demonstrate …
Peptidoglycan fragment release from Neisseria meningitidis
Neisseria meningitidis (meningococcus) is a symbiont of the human nasopharynx. On
occasion, meningococci disseminate from the nasopharynx to cause invasive disease …
occasion, meningococci disseminate from the nasopharynx to cause invasive disease …
Role of gonococcal neisserial surface protein A (NspA) in serum resistance and comparison of its factor H binding properties with those of its meningococcal …
LA Lewis, PA Rice, S Ram - Infection and Immunity, 2019 - Am Soc Microbiol
Neisseria gonorrhoeae, the causative agent of gonorrhea, has evolved several mechanisms
to subvert complement, including binding of the complement inhibitor factor H (FH). We …
to subvert complement, including binding of the complement inhibitor factor H (FH). We …
Transmigration of polymorphnuclear neutrophils and monocytes through the human blood-cerebrospinal fluid barrier after bacterial infection in vitro
U Steinmann, J Borkowski, H Wolburg… - Journal of …, 2013 - Springer
Background Bacterial invasion through the blood-cerebrospinal fluid barrier (BCSFB) during
bacterial meningitis causes secretion of proinflammatory cytokines/chemokines followed by …
bacterial meningitis causes secretion of proinflammatory cytokines/chemokines followed by …
A choroid plexus epithelial cell-based model of the human blood-cerebrospinal fluid barrier to study bacterial infection from the basolateral side
S Dinner, J Borkowski, C Stump-Guthier… - JoVE (Journal of …, 2016 - jove.com
The epithelial cells of the choroid plexus (CP), located in the ventricular system of the brain,
form the blood-cerebrospinal fluid barrier (BCSFB). The BCSFB functions in separating the …
form the blood-cerebrospinal fluid barrier (BCSFB). The BCSFB functions in separating the …
Three cases of invasive meningococcal disease caused by a capsule null locus strain circulating among healthy carriers in Burkina Faso
H Findlow, U Vogel, JE Mueller, A Curry… - The Journal of infectious …, 2007 - JSTOR
During reinforced surveillance of acute bacterial meningitis in Burkina Faso, meningococcal
strains of phenotype NG: NT: NST were isolated from cerebrospinal fluid samples from 3 …
strains of phenotype NG: NT: NST were isolated from cerebrospinal fluid samples from 3 …
Inhibition of the classical pathway of complement by meningococcal capsular polysaccharides
S Agarwal, S Vasudhev, RB DeOliveira… - The Journal of …, 2014 - journals.aai.org
Almost all invasive Neisseria meningitidis isolates express capsular polysaccharide. Ab is
required for complement-dependent killing of meningococci. Although alternative pathway …
required for complement-dependent killing of meningococci. Although alternative pathway …