Fluoroamphiphilic polymers exterminate multidrug-resistant Gram-negative ESKAPE pathogens while attenuating drug resistance
Q Zhou, K Li, K Wang, W Hong, J Chen, J Chai… - Science …, 2024 - science.org
ESKAPE pathogens are a panel of most recalcitrant bacteria that could “escape” the
treatment of antibiotics and exhibit high incidence of drug resistance. The emergence of …
treatment of antibiotics and exhibit high incidence of drug resistance. The emergence of …
Innovative strategies to overcome antimicrobial resistance and tolerance
MI Choudhary, U Römling, F Nadeem, HM Bilal… - Microorganisms, 2022 - mdpi.com
Antimicrobial resistance and tolerance are natural phenomena that arose due to
evolutionary adaptation of microorganisms against various xenobiotic agents. These …
evolutionary adaptation of microorganisms against various xenobiotic agents. These …
Outer-Membrane Permeabilization, LPS Transport Inhibition: Activity, Interactions, and Structures of Thanatin Derived Antimicrobial Peptides
SJ Abdullah, BTS Yan, N Palanivelu… - International Journal of …, 2024 - mdpi.com
Currently, viable antibiotics available to mitigate infections caused by drug-resistant Gram-
negative bacteria are highly limited. Thanatin, a 21-residue-long insect-derived antimicrobial …
negative bacteria are highly limited. Thanatin, a 21-residue-long insect-derived antimicrobial …
Imaging biomolecules in bilayers supported at electrode surfaces
P Pieta, S Sek, J Lipkowski - Current Opinion in Electrochemistry, 2023 - Elsevier
This short review describes our efforts to apply scanning tunneling microscopy and atomic
force microscopy to provide an understanding of the mechanism of phospholipid bilayer …
force microscopy to provide an understanding of the mechanism of phospholipid bilayer …
Enhanced synergistic antibacterial and antibiofilm efficacy of main-chain polysulfoniums with antibiotics by balancing charge density and amphiphilicity
Y Zhao, X Wang, Y Hu, J Zhao, M Sun… - ACS Applied Polymer …, 2023 - ACS Publications
Infection diseases caused by Gram-negative pathogens are exceedingly difficult to treat
because their characteristic outer membrane limits antibiotic entry. Herein, we report the …
because their characteristic outer membrane limits antibiotic entry. Herein, we report the …
[HTML][HTML] The natriuretic peptide receptor agonist osteocrin disperses Pseudomonas aeruginosa biofilm
M Louis, A Tahrioui, CJ Tremlett, T Clamens… - Biofilm, 2023 - Elsevier
Biofilms are highly tolerant to antimicrobials and host immune defense, enabling pathogens
to thrive in hostile environments. The diversity of microbial biofilm infections requires …
to thrive in hostile environments. The diversity of microbial biofilm infections requires …
The antimicrobial peptide Esc(1-21)-1c increases susceptibility of Pseudomonas aeruginosa to conventional antibiotics by decreasing the expression of the MexAB …
C Canè, B Casciaro, A Di Somma, MR Loffredo… - Frontiers in …, 2023 - frontiersin.org
Introduction: The increase in bacterial strains resistant to conventional antibiotics is an
alarming problem for human health and could lead to pandemics in the future. Among …
alarming problem for human health and could lead to pandemics in the future. Among …
Discovery and Characterization of a New Crustin Antimicrobial Peptide from Amphibalanus amphitrite
Crustins are an antimicrobial peptide (AMP) family that plays an important role in innate
immunity in crustaceans. It is important to discover new AMPs from natural sources to …
immunity in crustaceans. It is important to discover new AMPs from natural sources to …
Activities of a broad‐spectrum antimicrobial peptide analogue SAMP‐A4‐C8 and its combat against pneumonia in Staphylococcus aureus‐infected mice
R Li, P Hao, K Yin, Q Xu, S Ren, Y Zhao… - Journal of Peptide …, 2023 - Wiley Online Library
Antimicrobial peptides and their analogues have become substitutes for antibiotics in recent
years. The antimicrobial peptide analogue SAMP‐A4‐C8 (n‐octanoic‐VRLLRRRI) with high …
years. The antimicrobial peptide analogue SAMP‐A4‐C8 (n‐octanoic‐VRLLRRRI) with high …
Novel alligator cathelicidin As-CATH8 demonstrates anti-infective activity against clinically relevant and crocodylian bacterial pathogens
Host defense peptides (HDPs) represent an alternative way to address the emergence of
antibiotic resistance. Crocodylians are interesting species for the study of these molecules …
antibiotic resistance. Crocodylians are interesting species for the study of these molecules …