Unraveling the possibilities: Recent progress in DNA biosensing

M Yu, T He, Q Wang, C Cui - Biosensors, 2023 - mdpi.com
Due to the advantages of its numerous modification sites, predictable structure, high thermal
stability, and excellent biocompatibility, DNA is the ideal choice as a key component of …

Therapeutic potentials of microRNA-126 in cerebral ischemia

V Ebrahimi, SH Rastegar-Moghaddam… - Molecular …, 2023 - Springer
Stroke is a leading cause of death and disability worldwide. It is among the most common
neurological disorders with an 8–10% lifetime risk. Ischemic stroke accounts for about 85 …

Advanced Nanoarchitectonics of Drug Delivery Systems with Pyroptosis Inhibition for Noncancerous Disease Treatment

QY You, MD Hu, H Qian - Advanced Functional Materials, 2024 - Wiley Online Library
Programmed cell death (PCD) is a controlled and organized form of death regulated by
genes, allowing cells to adapt to their environment. Pyroptosis, a recently discovered type of …

DNA Tetrahedra-Based Delivery of MicroRNA-22 to Reduce Depressive Symptoms in Mice

Y Luo, X Yang, Y Du, Y Dou, W Cui, J Li… - … Applied Materials & …, 2023 - ACS Publications
Major depressive disorder (MDD) is a common illness with an increasing lifetime
prevalence. Thus, an increasing number of studies have investigated the association …

An immunocompetent environment unravels the proto-oncogenic role of miR-22

ML Centomo, M Vitiello, L Poliseno, PP Pandolfi - Cancers, 2022 - mdpi.com
Simple Summary Through their regulatory activity of gene expression, microRNAs have
been heavily implicated in the genesis of cancer. They can act both as promoters …

Non-Coding RNAs and Neurodegenerative Diseases: Information of their Roles in Apoptosis

M Valizadeh, E Derafsh, F Abdi Abyaneh… - Molecular …, 2024 - Springer
Apoptosis can be known as a key factor in the pathogenesis of neurodegenerative
disorders. In disease conditions, the rate of apoptosis expands and tissue damage may …

Recent advances in the roles of microRNA and microRNA-based diagnosis in neurodegenerative diseases

J Zhang, Z Chen, H Chen, Y Deng, S Li, L Jin - Biosensors, 2022 - mdpi.com
Neurodegenerative diseases manifest as progressive loss of neuronal structures and their
myelin sheaths and lead to substantial morbidity and mortality, especially in the elderly …

[HTML][HTML] Protective effects of EVs/exosomes derived from permanently growing human MSC on primary murine ALS motor neurons

T Gschwendtberger, N Thau-Habermann… - Neuroscience …, 2023 - Elsevier
In recent years, the neuroprotective potential of mesenchymal stroma-/stem-like cells (MSC)
as well as of MSC-derived extracellular vesicles (EVs) like exosomes has been intensively …

Molecular subtypes of epilepsy associated with post-surgical seizure recurrence

CE Hershberger, S Louis, RM Busch… - Brain …, 2023 - academic.oup.com
Approximately 50% of individuals who undergo resective epilepsy surgery experience
seizure recurrence. The heterogenous post-operative outcomes are not fully explained by …

Roles of exosomes in chronic rhinosinusitis: a systematic review

K Dżaman, K Czerwaty - International journal of molecular sciences, 2022 - mdpi.com
The pathophysiology of chronic rhinosinusitis (CRS) is multifactorial and not entirely clear.
The objective of the review was to examine the current state of knowledge concerning the …