[HTML][HTML] The biology and treatment of Merkel cell carcinoma: current understanding and research priorities

PW Harms, KL Harms, PS Moore… - Nature reviews Clinical …, 2018 - nature.com
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer associated with
advanced age and immunosuppression. Over the past decade, an association has been …

[HTML][HTML] Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches

N Hasan, A Nadaf, M Imran, U Jiba, A Sheikh… - Molecular cancer, 2023 - Springer
Skin cancer is a global threat to the healthcare system and is estimated to incline
tremendously in the next 20 years, if not diagnosed at an early stage. Even though it is …

Durable tumor regression and overall survival in patients with advanced Merkel cell carcinoma receiving pembrolizumab as first-line therapy

P Nghiem, S Bhatia, EJ Lipson… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE Merkel cell carcinoma (MCC) is an aggressive skin cancer often caused by the
Merkel cell polyomavirus. Clinical trials of programmed cell death-1 pathway inhibitors for …

[HTML][HTML] Immunotherapy for non-melanoma skin cancer

SZ Shalhout, KS Emerick, HL Kaufman… - Current Oncology …, 2021 - Springer
Abstract Purpose of Review The therapeutic landscape for non-melanoma skin cancer
(NMSC) has recently expanded with the development of effective and targeted …

Immune checkpoint inhibitors to treat cutaneous malignancies

DM Barrios, MH Do, GS Phillips, MA Postow… - Journal of the American …, 2020 - Elsevier
As the incidence of cutaneous malignancies continues to rise and their treatment with
immunotherapy expands, dermatologists and their patients are more likely to encounter …

[HTML][HTML] Identifying candidates for immunotherapy among patients with non-melanoma skin cancer: a review of the potential predictors of response

E Zelin, CA Maronese, A Dri, L Toffoli, N Di Meo… - Journal of Clinical …, 2022 - mdpi.com
Background: Non-melanoma skin cancer (NMSC) stands as an umbrella term for common
cutaneous malignancies, including basal cell carcinoma (BCC) and cutaneous squamous …

Patterns of distant metastases in 215 Merkel cell carcinoma patients: Implications for prognosis and surveillance

CW Lewis, J Qazi, DS Hippe, K Lachance… - Cancer …, 2020 - Wiley Online Library
Approximately one‐third of Merkel cell carcinoma (MCC) patients eventually develop distant
metastatic disease. Little is known about whether the location of the primary lesion is …

[HTML][HTML] Merkel cell carcinoma: New trends

EM Zwijnenburg, SFK Lubeek, JEM Werner, AL Amir… - Cancers, 2021 - mdpi.com
Simple Summary In this review, we discuss a rare skin cancer that occurs mostly in elderly
people called “Merkel cell carcinoma”(MCC). The incidence is increasing due to ageing of …

[HTML][HTML] Merkel cell carcinoma: therapeutic update and emerging therapies

A Villani, G Fabbrocini, C Costa… - Dermatology and …, 2019 - Springer
Merkel cell carcinoma (MCC) is a rare but highly aggressive neuroendocrine skin cancer
whose incidence has almost doubled in recent decades. Risk factors for MCC include age> …

[HTML][HTML] Immune checkpoint inhibition in non-melanoma skin Cancer: a review of current evidence

CJ Stonesifer, AR Djavid, JM Grimes, AE Khaleel… - Frontiers in …, 2021 - frontiersin.org
Recent advances in the field of immuno-oncology have translated into breakthrough
treatments for many solid and hematological malignancies. The prior study of …