The blood–brain barrier: structure, regulation, and drug delivery

D Wu, Q Chen, X Chen, F Han, Z Chen… - Signal Transduction and …, 2023 - nature.com
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …

[HTML][HTML] Inorganic nanomaterials with rapid clearance for biomedical applications

X Wang, X Zhong, J Li, Z Liu, L Cheng - Chemical Society Reviews, 2021 - pubs.rsc.org
Inorganic nanomaterials that have inherently exceptional physicochemical properties (eg,
catalytic, optical, thermal, electrical, or magnetic performance) that can provide desirable …

Nanodelivery of nucleic acids

BB Mendes, J Conniot, A Avital, D Yao… - Nature reviews …, 2022 - nature.com
There is growing need for a safe, efficient, specific and non-pathogenic means for delivery of
gene therapy materials. Nanomaterials for nucleic acid delivery offer an unprecedented …

Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

[HTML][HTML] Recent advances in biomedical engineering of nano-hydroxyapatite including dentistry, cancer treatment and bone repair

M Du, J Chen, K Liu, H Xing, C Song - Composites Part B: Engineering, 2021 - Elsevier
Hydroxyapatite (HAp) has significant biological activity, degradability, and osteoconductivity.
In recent decades, it has been widely used in dentistry, anti-tumour drug carriers, and …

Nanocatalytic medicine

B Yang, Y Chen, J Shi - Advanced materials, 2019 - Wiley Online Library
Catalysis and medicine are often considered as two independent research fields with their
own respective scientific phenomena. Promoted by recent advances in nanochemistry, large …

[HTML][HTML] Unveiling the active sites on ferrihydrite with apparent catalase-like activity for potentiating radiotherapy

R Zhang, L Chen, Q Liang, J Xi, H Zhao, Y Jin, X Gao… - Nano Today, 2021 - Elsevier
The use of catalase-like nanozymes in relieving tumor hypoxia has been a promising
strategy for adjuvant radiotherapy, yet their catalytic mechanism and toxic potential remain …

Emerging ultrasmall luminescent nanoprobes for in vivo bioimaging

S Li, J Wei, Q Yao, X Song, J Xie, H Yang - Chemical Society Reviews, 2023 - pubs.rsc.org
Photoluminescence (PL) imaging has become a fundamental tool in disease diagnosis,
therapeutic evaluation, and surgical navigation applications. However, it remains a big …

ZnO nanomaterials: Green synthesis, toxicity evaluation and new insights in biomedical applications

R Verma, S Pathak, AK Srivastava, S Prawer… - Journal of Alloys and …, 2021 - Elsevier
Nanotechnology has engraved new insight into the material sciences and zinc oxide
nanomaterials (ZnO NMs) are one of the most extensively used materials in healthcare and …

Dependence of nanoparticle toxicity on their physical and chemical properties

A Sukhanova, S Bozrova, P Sokolov… - Nanoscale research …, 2018 - Springer
Studies on the methods of nanoparticle (NP) synthesis, analysis of their characteristics, and
exploration of new fields of their applications are at the forefront of modern nanotechnology …